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Risk of HIV transmission from patients on antiretroviral therapy: A position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy

Albert, Jan; Berglund, Torsten; Gisslen, Magnus; Groon, Peter; Sonnerborg, Anders; Tegnell, Anders; Alexandersson, Anders; Berggren, Ingela; Blaxhult, Anders and Brytting, Maria, et al. (2014) In Scandinavian Journal of Infectious Diseases 46(10). p.673-677
Abstract
The modern medical treatment of HIV with antiretroviral therapy (ART) has drastically reduced the morbidity and mortality in patients infected with this virus. ART has also been shown to reduce the transmission risk from individual patients as well as the spread of the infection at the population level. This position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy is based on a workshop organized in the fall of 2012. It summarizes the latest research and knowledge on the risk of HIV transmission from patients on ART, with a focus on the risk of sexual transmission. The risk of transmission via shared injection equipment among intravenous drug users is also examined, as is the risk of... (More)
The modern medical treatment of HIV with antiretroviral therapy (ART) has drastically reduced the morbidity and mortality in patients infected with this virus. ART has also been shown to reduce the transmission risk from individual patients as well as the spread of the infection at the population level. This position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy is based on a workshop organized in the fall of 2012. It summarizes the latest research and knowledge on the risk of HIV transmission from patients on ART, with a focus on the risk of sexual transmission. The risk of transmission via shared injection equipment among intravenous drug users is also examined, as is the risk of mother-to-child transmission. Based on current knowledge, the risk of transmission through vaginal or anal intercourse involving the use of a condom has been judged to be minimal, provided that the person infected with HIV fulfils the criteria for effective ART. This probably also applies to unprotected intercourse, provided that no other sexually transmitted infections are present, although it is not currently possible to fully support this conclusion with direct scientific evidence. ART is judged to markedly reduce the risk of blood-borne transmission between people who share injection equipment. Finally, the risk of transmission from mother to child is very low, provided that ART is started well in advance of delivery. (Less)
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publication status
published
subject
keywords
HIV transmission therapy
in
Scandinavian Journal of Infectious Diseases
volume
46
issue
10
pages
673 - 677
publisher
Informa Healthcare
external identifiers
  • wos:000342202800001
  • scopus:84907143424
ISSN
1651-1980
DOI
10.3109/00365548.2014.926565
language
English
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yes
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9ee12757-6447-4e94-a1a3-d1e1b06d55ce (old id 4699735)
date added to LUP
2014-10-23 08:00:44
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2017-04-09 04:07:13
@article{9ee12757-6447-4e94-a1a3-d1e1b06d55ce,
  abstract     = {The modern medical treatment of HIV with antiretroviral therapy (ART) has drastically reduced the morbidity and mortality in patients infected with this virus. ART has also been shown to reduce the transmission risk from individual patients as well as the spread of the infection at the population level. This position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy is based on a workshop organized in the fall of 2012. It summarizes the latest research and knowledge on the risk of HIV transmission from patients on ART, with a focus on the risk of sexual transmission. The risk of transmission via shared injection equipment among intravenous drug users is also examined, as is the risk of mother-to-child transmission. Based on current knowledge, the risk of transmission through vaginal or anal intercourse involving the use of a condom has been judged to be minimal, provided that the person infected with HIV fulfils the criteria for effective ART. This probably also applies to unprotected intercourse, provided that no other sexually transmitted infections are present, although it is not currently possible to fully support this conclusion with direct scientific evidence. ART is judged to markedly reduce the risk of blood-borne transmission between people who share injection equipment. Finally, the risk of transmission from mother to child is very low, provided that ART is started well in advance of delivery.},
  author       = {Albert, Jan and Berglund, Torsten and Gisslen, Magnus and Groon, Peter and Sonnerborg, Anders and Tegnell, Anders and Alexandersson, Anders and Berggren, Ingela and Blaxhult, Anders and Brytting, Maria and Carlander, Christina and Carlson, Johan and Flamholc, Leo and Follin, Per and Haggar, Axana and Hansdotter, Frida and Josephson, Filip and Karlstrom, Olle and Liljeros, Fredrik and Naver, Lars and Pettersson, Karin and Johansson, Veronica Svedhem and Svennerholm, Bo and Tunback, Petra and Widgren, Katarina},
  issn         = {1651-1980},
  keyword      = {HIV transmission therapy},
  language     = {eng},
  number       = {10},
  pages        = {673--677},
  publisher    = {Informa Healthcare},
  series       = {Scandinavian Journal of Infectious Diseases},
  title        = {Risk of HIV transmission from patients on antiretroviral therapy: A position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy},
  url          = {http://dx.doi.org/10.3109/00365548.2014.926565},
  volume       = {46},
  year         = {2014},
}