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Toward classification criteria for early osteoarthritis of the knee

Luyten, F. P.; Bierma-Zeinstra, S; Dell'Accio, F.; Kraus, V. B.; Nakata, K.; Sekiya, I.; Arden, N. K. and Lohmander, L. S. LU (2018) In Seminars in Arthritis and Rheumatism 47(4). p.457-463
Abstract

Objective: To propose draft classification criteria for early stage osteoarthritis (OA) of the knee for use in a primary care setting. Methods: A group of basic scientists, physician-scientists, rheumatologists, orthopedic surgeons, and physiotherapists in a workshop setting discussed potential classification criteria for early osteoarthritis of the knee. The workshop was divided into sessions around relevant topics with short state of the art presentations followed by breakout sessions, consensus discussions, and consolidation into a consensus document. Results: Three classes of criteria were agreed: (1) Pain, symptoms/signs, self-reported function, and quality of life using tools such as KOOS: scoring ≤85% in at least 2 out of these 4... (More)

Objective: To propose draft classification criteria for early stage osteoarthritis (OA) of the knee for use in a primary care setting. Methods: A group of basic scientists, physician-scientists, rheumatologists, orthopedic surgeons, and physiotherapists in a workshop setting discussed potential classification criteria for early osteoarthritis of the knee. The workshop was divided into sessions around relevant topics with short state of the art presentations followed by breakout sessions, consensus discussions, and consolidation into a consensus document. Results: Three classes of criteria were agreed: (1) Pain, symptoms/signs, self-reported function, and quality of life using tools such as KOOS: scoring ≤85% in at least 2 out of these 4 categories; (2) Clinical examination: at least 1 present out of joint line tenderness or crepitus; (3) Knee radiographs: Kellgren & Lawrence (KL) grade of 0 or 1. MRI is at present not recommended as an aid to identify or define early OA in routine clinical practice or primary care, in light of the absence of validated consensus criteria and the high population prevalence of structural joint changes detected by this method. Biomarkers may have future utility in early OA classification, but no individual or set of biomarkers is yet robust enough. Conclusion: Based on our consensus proposal, draft classification criteria for early OA of the knee for use in clinical studies should include patient reported outcomes such as pain and function, together with clinical signs and KL grade 0-1 on radiographs.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Classification criteria, Early osteoarthritis, Knee
in
Seminars in Arthritis and Rheumatism
volume
47
issue
4
pages
457 - 463
publisher
W.B. Saunders Co.
external identifiers
  • scopus:85029221947
ISSN
0049-0172
DOI
10.1016/j.semarthrit.2017.08.006
language
English
LU publication?
yes
id
46c17b9b-1b34-4319-8bb0-9af99d6c3b3b
date added to LUP
2017-10-11 08:39:10
date last changed
2018-04-15 04:47:58
@article{46c17b9b-1b34-4319-8bb0-9af99d6c3b3b,
  abstract     = {<p>Objective: To propose draft classification criteria for early stage osteoarthritis (OA) of the knee for use in a primary care setting. Methods: A group of basic scientists, physician-scientists, rheumatologists, orthopedic surgeons, and physiotherapists in a workshop setting discussed potential classification criteria for early osteoarthritis of the knee. The workshop was divided into sessions around relevant topics with short state of the art presentations followed by breakout sessions, consensus discussions, and consolidation into a consensus document. Results: Three classes of criteria were agreed: (1) Pain, symptoms/signs, self-reported function, and quality of life using tools such as KOOS: scoring ≤85% in at least 2 out of these 4 categories; (2) Clinical examination: at least 1 present out of joint line tenderness or crepitus; (3) Knee radiographs: Kellgren &amp; Lawrence (KL) grade of 0 or 1. MRI is at present not recommended as an aid to identify or define early OA in routine clinical practice or primary care, in light of the absence of validated consensus criteria and the high population prevalence of structural joint changes detected by this method. Biomarkers may have future utility in early OA classification, but no individual or set of biomarkers is yet robust enough. Conclusion: Based on our consensus proposal, draft classification criteria for early OA of the knee for use in clinical studies should include patient reported outcomes such as pain and function, together with clinical signs and KL grade 0-1 on radiographs.</p>},
  author       = {Luyten, F. P. and Bierma-Zeinstra, S and Dell'Accio, F. and Kraus, V. B. and Nakata, K. and Sekiya, I. and Arden, N. K. and Lohmander, L. S.},
  issn         = {0049-0172},
  keyword      = {Classification criteria,Early osteoarthritis,Knee},
  language     = {eng},
  number       = {4},
  pages        = {457--463},
  publisher    = {W.B. Saunders Co.},
  series       = {Seminars in Arthritis and Rheumatism},
  title        = {Toward classification criteria for early osteoarthritis of the knee},
  url          = {http://dx.doi.org/10.1016/j.semarthrit.2017.08.006},
  volume       = {47},
  year         = {2018},
}