Production of protein HC by human fetal liver explants
(1978) In Biochimica et Biophysica Acta 542(3). p.14-506- Abstract
Human fetal lever explants were found to secrete protein HC into the medium in molar amounts comparable to those of albumin, alpha 1-antitrypsin and orosomucoid. Incorporation of a radioactive amino acid from the medium into the secreted protein HC demonstrated de novo synthesis. The secreted protein HC had the same size and electrophoretic mobility as protein HC of plasma and urine and gave a reaction of immunochemical identity with the protein in these biological fluids.
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- author
- Tejler, L ; Eriksson, S LU ; Grubb, A LU and Åstedt, B
- organization
- publishing date
- 1978
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Alpha-Globulins, Antigens/analysis, Culture Media, Glycoproteins/biosynthesis, Humans, Liver/embryology, Molecular Weight, Organ Culture Techniques
- in
- Biochimica et Biophysica Acta
- volume
- 542
- issue
- 3
- pages
- 14 - 506
- publisher
- Elsevier
- external identifiers
-
- scopus:0018116013
- pmid:687667
- ISSN
- 0006-3002
- DOI
- 10.1016/0304-4165(78)90380-x
- language
- English
- LU publication?
- yes
- id
- 470c414e-0c20-486e-839c-e39ae14e7e52
- date added to LUP
- 2021-10-16 19:29:06
- date last changed
- 2024-01-12 02:55:32
@article{470c414e-0c20-486e-839c-e39ae14e7e52, abstract = {{<p>Human fetal lever explants were found to secrete protein HC into the medium in molar amounts comparable to those of albumin, alpha 1-antitrypsin and orosomucoid. Incorporation of a radioactive amino acid from the medium into the secreted protein HC demonstrated de novo synthesis. The secreted protein HC had the same size and electrophoretic mobility as protein HC of plasma and urine and gave a reaction of immunochemical identity with the protein in these biological fluids.</p>}}, author = {{Tejler, L and Eriksson, S and Grubb, A and Åstedt, B}}, issn = {{0006-3002}}, keywords = {{Alpha-Globulins; Antigens/analysis; Culture Media; Glycoproteins/biosynthesis; Humans; Liver/embryology; Molecular Weight; Organ Culture Techniques}}, language = {{eng}}, number = {{3}}, pages = {{14--506}}, publisher = {{Elsevier}}, series = {{Biochimica et Biophysica Acta}}, title = {{Production of protein HC by human fetal liver explants}}, url = {{http://dx.doi.org/10.1016/0304-4165(78)90380-x}}, doi = {{10.1016/0304-4165(78)90380-x}}, volume = {{542}}, year = {{1978}}, }