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The specificity triad: notions of disease and therapeutic specificity in biomedical reasoning

Mulinari, Shai LU (2014) In Philosophy Ethics and Humanities in Medicine 9(1).
Abstract
Biomedicine is typically defined as the branch of medicine that is based on the principles of biology and biochemistry. A central tenet for biomedicine is the notion of disease and therapeutic specificity, i.e. the idea of tailored treatments for discrete disorders underpinned by specific pathologies. The present paper is concerned with how notions of disease and therapeutic specificity guide biomedical reasoning. To that end, the author proposes a model - the specificity triad - that draws on late philosopher and physician Ludwik Fleck's concept of "style of thought" to offer a frame for investigating the intricate process through which links between disorders, mechanisms, and therapeutics are established by biomedicine. Next by applying... (More)
Biomedicine is typically defined as the branch of medicine that is based on the principles of biology and biochemistry. A central tenet for biomedicine is the notion of disease and therapeutic specificity, i.e. the idea of tailored treatments for discrete disorders underpinned by specific pathologies. The present paper is concerned with how notions of disease and therapeutic specificity guide biomedical reasoning. To that end, the author proposes a model - the specificity triad - that draws on late philosopher and physician Ludwik Fleck's concept of "style of thought" to offer a frame for investigating the intricate process through which links between disorders, mechanisms, and therapeutics are established by biomedicine. Next by applying the specificity triad model to scrutinize research efforts in two discrete areas of medicine--psychiatry and regenerative medicine--this paper seeks to stimulate pertinent discussions in and about biomedicine. These include discussions on the ambiguous epistemic status of psychiatry within contemporary biomedicine, as well as the relationship between developmental biology -- historically relatively disjointed from biomedical enterprise -- and the burgeoning field of regenerative medicine. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Specificity, Style of thought, Biomedicine, Fleck, Regenerative medicine, Developmental biology, Psychiatry, Neuroscience
in
Philosophy Ethics and Humanities in Medicine
volume
9
issue
1
publisher
BioMed Central
external identifiers
  • pmid:25326797
  • scopus:84925298414
ISSN
1747-5341
DOI
10.1186/1747-5341-9-14
language
English
LU publication?
yes
id
f6eec282-c678-4fdc-b47b-aee3a6e81305 (old id 4730446)
date added to LUP
2014-10-24 16:10:12
date last changed
2017-09-19 13:23:11
@article{f6eec282-c678-4fdc-b47b-aee3a6e81305,
  abstract     = {Biomedicine is typically defined as the branch of medicine that is based on the principles of biology and biochemistry. A central tenet for biomedicine is the notion of disease and therapeutic specificity, i.e. the idea of tailored treatments for discrete disorders underpinned by specific pathologies. The present paper is concerned with how notions of disease and therapeutic specificity guide biomedical reasoning. To that end, the author proposes a model - the specificity triad - that draws on late philosopher and physician Ludwik Fleck's concept of "style of thought" to offer a frame for investigating the intricate process through which links between disorders, mechanisms, and therapeutics are established by biomedicine. Next by applying the specificity triad model to scrutinize research efforts in two discrete areas of medicine--psychiatry and regenerative medicine--this paper seeks to stimulate pertinent discussions in and about biomedicine. These include discussions on the ambiguous epistemic status of psychiatry within contemporary biomedicine, as well as the relationship between developmental biology -- historically relatively disjointed from biomedical enterprise -- and the burgeoning field of regenerative medicine.},
  articleno    = {14},
  author       = {Mulinari, Shai},
  issn         = {1747-5341},
  keyword      = {Specificity,Style of thought,Biomedicine,Fleck,Regenerative medicine,Developmental biology,Psychiatry,Neuroscience},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Philosophy Ethics and Humanities in Medicine},
  title        = {The specificity triad: notions of disease and therapeutic specificity in biomedical reasoning},
  url          = {http://dx.doi.org/10.1186/1747-5341-9-14},
  volume       = {9},
  year         = {2014},
}