Mammography and Osteoporosis Screening-Clinical Risk Factors and Their Association With Digital X-Ray Radiogrammetry Bone Mineral Density.
(2015) In Journal of Clinical Densitometry 18(1). p.22-29- Abstract
- The aim of this study was to study the association between digital X-ray radiogrammetry (DXR) T-score and clinical risk factors for osteoporosis. Women were recruited 2 d per wk at a single mammography screening center between year 2010 and 2012. Included women answered a questionnaire about risk factors for osteoporosis, and a radiograph of the nondominant hand was obtained for DXR analysis. Univariate associations between DXR T-score and risk factors were examined. A generalized linear regression model was fitted to independent variables with univariate associations at p < 0.05. The multivariable model was reduced through manual backward elimination, with p > 0.1 as the exclusion criterion. Seventy-six percent of the women chose to... (More)
- The aim of this study was to study the association between digital X-ray radiogrammetry (DXR) T-score and clinical risk factors for osteoporosis. Women were recruited 2 d per wk at a single mammography screening center between year 2010 and 2012. Included women answered a questionnaire about risk factors for osteoporosis, and a radiograph of the nondominant hand was obtained for DXR analysis. Univariate associations between DXR T-score and risk factors were examined. A generalized linear regression model was fitted to independent variables with univariate associations at p < 0.05. The multivariable model was reduced through manual backward elimination, with p > 0.1 as the exclusion criterion. Seventy-six percent of the women chose to participate in the study (n = 8810). The difference in number of daily mammograms performed on study vs nonstudy days was not significant. All univariate associations between DXR T-score and potential risk factors were highly significant. The multivariable model included height, weight, age, right-handedness, menopause before age 45, alcohol consumption, cortisone treatment, rheumatic disease, and age × smoking status. The coefficient of determination of the model was 0.37. The association between risk factors for osteoporosis and DXR T-score is similar to previously reported associations with dual-energy X-ray absorptiometry. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4737335
- author
- Wilczek, Michael L ; Nielsen, Christel LU ; Kälvesten, Johan ; Algulin, Jakob and Brismar, Torkel B
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Clinical Densitometry
- volume
- 18
- issue
- 1
- pages
- 22 - 29
- publisher
- Elsevier
- external identifiers
-
- pmid:25294740
- wos:000348970300006
- scopus:84921860848
- pmid:25294740
- ISSN
- 1094-6950
- DOI
- 10.1016/j.jocd.2014.07.007
- language
- English
- LU publication?
- yes
- id
- a912e195-7607-4dd0-9fba-c752a79bec9f (old id 4737335)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25294740?dopt=Abstract
- date added to LUP
- 2016-04-01 10:00:52
- date last changed
- 2022-04-12 01:09:21
@article{a912e195-7607-4dd0-9fba-c752a79bec9f, abstract = {{The aim of this study was to study the association between digital X-ray radiogrammetry (DXR) T-score and clinical risk factors for osteoporosis. Women were recruited 2 d per wk at a single mammography screening center between year 2010 and 2012. Included women answered a questionnaire about risk factors for osteoporosis, and a radiograph of the nondominant hand was obtained for DXR analysis. Univariate associations between DXR T-score and risk factors were examined. A generalized linear regression model was fitted to independent variables with univariate associations at p < 0.05. The multivariable model was reduced through manual backward elimination, with p > 0.1 as the exclusion criterion. Seventy-six percent of the women chose to participate in the study (n = 8810). The difference in number of daily mammograms performed on study vs nonstudy days was not significant. All univariate associations between DXR T-score and potential risk factors were highly significant. The multivariable model included height, weight, age, right-handedness, menopause before age 45, alcohol consumption, cortisone treatment, rheumatic disease, and age × smoking status. The coefficient of determination of the model was 0.37. The association between risk factors for osteoporosis and DXR T-score is similar to previously reported associations with dual-energy X-ray absorptiometry.}}, author = {{Wilczek, Michael L and Nielsen, Christel and Kälvesten, Johan and Algulin, Jakob and Brismar, Torkel B}}, issn = {{1094-6950}}, language = {{eng}}, number = {{1}}, pages = {{22--29}}, publisher = {{Elsevier}}, series = {{Journal of Clinical Densitometry}}, title = {{Mammography and Osteoporosis Screening-Clinical Risk Factors and Their Association With Digital X-Ray Radiogrammetry Bone Mineral Density.}}, url = {{http://dx.doi.org/10.1016/j.jocd.2014.07.007}}, doi = {{10.1016/j.jocd.2014.07.007}}, volume = {{18}}, year = {{2015}}, }