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High-attenuation artifact reduction in breast tomosynthesis using a novel reconstruction algorithm

Dustler, Magnus LU ; Wicklein, Julia; Förnvik, Hannie LU ; Boita, Joana; Bakic, Predrag and Lång, Kristina LU (2019) In European Journal of Radiology 116. p.21-26
Abstract

Purpose: To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT)using a novel artifact-reducing reconstruction algorithm in specimen radiography. Methods and Materials: The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation,... (More)

Purpose: To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT)using a novel artifact-reducing reconstruction algorithm in specimen radiography. Methods and Materials: The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation, and combined into an artifact-reduced reconstruction. Standard and artifact-reduced BT-algorithms were compared visually and quantitatively using clinical images of mastectomy specimens and a physical anthropomorphic phantom. Six readers independently assessed the visibility of the lesion with and without artifact-reduction in a side-by-side comparison. A quantitative analysis was performed, comparing the signal-difference to background ratio (SDBR)and artifact spread function (ASF)between the two reconstruction methods. Results: The magnitude of out-of-plane artifacts was clearly reduced with the novel reconstruction compared to BT-images without artifact reduction. Lesion masking by artifacts was largely averted; tumour visibility was comparable to standard BT images without a needle. In 76 ± 8% (standard deviation)of cases overall, readers could confidently state needle location. The same figure was 94 ± 6% for whole mastectomy cases, compared to 62 ± 17% for partial mastectomies. With metal artifact reduction, SDBR increased by 97% in the phantom, and by 69% in the mastectomies. The artifact spread function was substantially narrower. Conclusion: Artifact reduction in BT using a novel reconstruction method enables qualitatively and quantitatively improved clinical use of BT when metal artifacts can be a limiting factor such as in tomosynthesis-guided biopsy.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Artifact reduction, Breast imaging, Breast tomosynthesis, Image reconstruction, Mammography
in
European Journal of Radiology
volume
116
pages
6 pages
publisher
Elsevier
external identifiers
  • scopus:85064731563
ISSN
0720-048X
DOI
10.1016/j.ejrad.2019.04.014
language
English
LU publication?
yes
id
4777e5b7-b389-4323-810c-6d5845afbb4b
date added to LUP
2019-05-02 14:54:34
date last changed
2019-05-28 03:57:14
@article{4777e5b7-b389-4323-810c-6d5845afbb4b,
  abstract     = {<p>Purpose: To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT)using a novel artifact-reducing reconstruction algorithm in specimen radiography. Methods and Materials: The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation, and combined into an artifact-reduced reconstruction. Standard and artifact-reduced BT-algorithms were compared visually and quantitatively using clinical images of mastectomy specimens and a physical anthropomorphic phantom. Six readers independently assessed the visibility of the lesion with and without artifact-reduction in a side-by-side comparison. A quantitative analysis was performed, comparing the signal-difference to background ratio (SDBR)and artifact spread function (ASF)between the two reconstruction methods. Results: The magnitude of out-of-plane artifacts was clearly reduced with the novel reconstruction compared to BT-images without artifact reduction. Lesion masking by artifacts was largely averted; tumour visibility was comparable to standard BT images without a needle. In 76 ± 8% (standard deviation)of cases overall, readers could confidently state needle location. The same figure was 94 ± 6% for whole mastectomy cases, compared to 62 ± 17% for partial mastectomies. With metal artifact reduction, SDBR increased by 97% in the phantom, and by 69% in the mastectomies. The artifact spread function was substantially narrower. Conclusion: Artifact reduction in BT using a novel reconstruction method enables qualitatively and quantitatively improved clinical use of BT when metal artifacts can be a limiting factor such as in tomosynthesis-guided biopsy.</p>},
  author       = {Dustler, Magnus and Wicklein, Julia and Förnvik, Hannie and Boita, Joana and Bakic, Predrag and Lång, Kristina},
  issn         = {0720-048X},
  keyword      = {Artifact reduction,Breast imaging,Breast tomosynthesis,Image reconstruction,Mammography},
  language     = {eng},
  pages        = {21--26},
  publisher    = {Elsevier},
  series       = {European Journal of Radiology},
  title        = {High-attenuation artifact reduction in breast tomosynthesis using a novel reconstruction algorithm},
  url          = {http://dx.doi.org/10.1016/j.ejrad.2019.04.014},
  volume       = {116},
  year         = {2019},
}