Vascular ageing in relation to chronological and self‑perceived age: A Swedish population‑based study
(2022) ARTERY 22 Conference In Artery Research 29. p.36-36- Abstract
- Background: Chronological age is a key clinical determinant of
aortic stiffness. Self-perceived age (SPA) is a strong predictor of
well-being and long-term health. We aimed to investigate the
association between SPA, chronological age, and aortic stiffness
(vascular ageing) in the general population.
Methods: Cross-sectional analysis of a population-based study,
Malmö Offspring Study (n=3563). Mean age 42±14 years,
age range 18–74, 53.4% women. Participants completed aself-administered questionnaire related to SPA compared to same aged/sex peers graded: younger, no difference, older. Aortic stiffness was assessed by carotid-femoral pulse wave velocity (c-f PWV; SphygmoCor), defined as > 10 m/s. Logistic... (More) - Background: Chronological age is a key clinical determinant of
aortic stiffness. Self-perceived age (SPA) is a strong predictor of
well-being and long-term health. We aimed to investigate the
association between SPA, chronological age, and aortic stiffness
(vascular ageing) in the general population.
Methods: Cross-sectional analysis of a population-based study,
Malmö Offspring Study (n=3563). Mean age 42±14 years,
age range 18–74, 53.4% women. Participants completed aself-administered questionnaire related to SPA compared to same aged/sex peers graded: younger, no difference, older. Aortic stiffness was assessed by carotid-femoral pulse wave velocity (c-f PWV; SphygmoCor), defined as > 10 m/s. Logistic regression models were adjusted for chronological age and sex.
Results: Aortic stiffness occurred in 234 (6.6%) subjects. Mean age decreased gradually between all three SPA categories, with the highest mean age observed in subjects who perceived themselves as younger than same-aged/sex peers (49±1 vs. 40±1 vs. 32±1 years, p0.40, p=0.002). Adjustment for sex did not change this association (OR: 0.67, p=0.003). Upon adjustment for sex and chronological older SPA was associated with almost twofold increased likelihood of aortic stiffness (OR: 1.97, p=0.038). Sex-stratification demonstrated a stronger 2.5-fold likelihood of aortic stiffness in men (OR: 2.50, p=0.042), but no significant association in women (OR: 1.46,
p=0.43).
Conclusions: A negative self-perceived age (feeling older than same aged/sex peers) is associated with a 2.5-fold increased likelihood of aortic stiffness (vascular ageing) in men when adjusted for chronological age, but not in women. (Less)
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https://lup.lub.lu.se/record/477f10f7-2acf-47d8-94d2-1b30ec046b0b
- author
- Johansson, Madeleine LU and Nilsson, Peter M LU
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Aortic stiffness, Vascular ageing, population studies, ageing
- in
- Artery Research
- volume
- 29
- article number
- P.104
- pages
- 36 - 36
- publisher
- Elsevier
- conference name
- ARTERY 22 Conference
- conference location
- Nancy, France
- conference dates
- 2022-10-19 - 2022-10-22
- external identifiers
-
- pmid:36776700
- ISSN
- 1872-9312
- DOI
- 10.1007/s44200-022-00028-8
- project
- Vascular Ageing and Arterial Stiffness in the Swedish Population
- language
- English
- LU publication?
- yes
- id
- 477f10f7-2acf-47d8-94d2-1b30ec046b0b
- date added to LUP
- 2023-02-21 02:31:30
- date last changed
- 2024-06-15 15:32:50
@misc{477f10f7-2acf-47d8-94d2-1b30ec046b0b, abstract = {{Background: Chronological age is a key clinical determinant of<br/>aortic stiffness. Self-perceived age (SPA) is a strong predictor of<br/>well-being and long-term health. We aimed to investigate the<br/>association between SPA, chronological age, and aortic stiffness<br/>(vascular ageing) in the general population.<br/><br/>Methods: Cross-sectional analysis of a population-based study,<br/>Malmö Offspring Study (n=3563). Mean age 42±14 years,<br/>age range 18–74, 53.4% women. Participants completed aself-administered questionnaire related to SPA compared to same aged/sex peers graded: younger, no difference, older. Aortic stiffness was assessed by carotid-femoral pulse wave velocity (c-f PWV; SphygmoCor), defined as > 10 m/s. Logistic regression models were adjusted for chronological age and sex.<br/><br/>Results: Aortic stiffness occurred in 234 (6.6%) subjects. Mean age decreased gradually between all three SPA categories, with the highest mean age observed in subjects who perceived themselves as younger than same-aged/sex peers (49±1 vs. 40±1 vs. 32±1 years, p0.40, p=0.002). Adjustment for sex did not change this association (OR: 0.67, p=0.003). Upon adjustment for sex and chronological older SPA was associated with almost twofold increased likelihood of aortic stiffness (OR: 1.97, p=0.038). Sex-stratification demonstrated a stronger 2.5-fold likelihood of aortic stiffness in men (OR: 2.50, p=0.042), but no significant association in women (OR: 1.46,<br/>p=0.43).<br/><br/>Conclusions: A negative self-perceived age (feeling older than same aged/sex peers) is associated with a 2.5-fold increased likelihood of aortic stiffness (vascular ageing) in men when adjusted for chronological age, but not in women.}}, author = {{Johansson, Madeleine and Nilsson, Peter M}}, issn = {{1872-9312}}, keywords = {{Aortic stiffness; Vascular ageing; population studies; ageing}}, language = {{eng}}, note = {{Conference Abstract}}, pages = {{36--36}}, publisher = {{Elsevier}}, series = {{Artery Research}}, title = {{Vascular ageing in relation to chronological and self‑perceived age: A Swedish population‑based study}}, url = {{http://dx.doi.org/10.1007/s44200-022-00028-8}}, doi = {{10.1007/s44200-022-00028-8}}, volume = {{29}}, year = {{2022}}, }