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Five-region study finds no evidence of undiagnosed type 2 diabetes in Swedish 11- to 13-year-olds

Berhan, Yonas T. ; Mollsten, Anna ; Carlsson, Annelie LU orcid ; Hogberg, Lotta ; Ivarsson, Anneli and Dahlquist, Gisela (2014) In Acta Pædiatrica 103(10). p.1078-1082
Abstract
AimChildhood obesity is now an established public health problem in most developed countries, and there is concern about a parallel increase of type 2 diabetes. The aim of this study was to estimate the prevalence of undiagnosed type 2 diabetes in overweight Swedish school children from 11 to 13years of age. MethodsBody mass index (BMI) was measured in 5528 schoolchildren in the 6th grade, from 11 to 13years of age, in five different regions in Sweden. Overweight was defined by international age- and sex-specific BMI cut-offs, corresponding to adult BMI cut-offs of 25kg/m(2) at 18years of age (ISO-BMI 25, n=1275). Haemoglobin A1c (HbA1c) was measured in 1126 children with ISO-BMI 25. Children with a Diabetes Control and Complications Trial... (More)
AimChildhood obesity is now an established public health problem in most developed countries, and there is concern about a parallel increase of type 2 diabetes. The aim of this study was to estimate the prevalence of undiagnosed type 2 diabetes in overweight Swedish school children from 11 to 13years of age. MethodsBody mass index (BMI) was measured in 5528 schoolchildren in the 6th grade, from 11 to 13years of age, in five different regions in Sweden. Overweight was defined by international age- and sex-specific BMI cut-offs, corresponding to adult BMI cut-offs of 25kg/m(2) at 18years of age (ISO-BMI 25, n=1275). Haemoglobin A1c (HbA1c) was measured in 1126 children with ISO-BMI 25. Children with a Diabetes Control and Complications Trial aligned HbA1c 6.1% on two occasions underwent an oral glucose tolerance test (OGTT) to establish the diabetes diagnosis. ResultsOf 1126 children with ISO-BMI 25, 24 (2.1%) had at least one HbA1c value 6.1%. Three of them had HbA1c 6.1% on two occasions, and all of them had a normal OGTT. ConclusionIn this cross-sectional, population-based screening study of a high-risk group of 11- to 13-year-old Swedish school children, we found no indication of undiagnosed diabetes or impaired glucose tolerance. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Childhood obesity, Diabetes mellitus type 2, Epidemiology
in
Acta Pædiatrica
volume
103
issue
10
pages
1078 - 1082
publisher
Wiley-Blackwell
external identifiers
  • wos:000342753400022
  • pmid:24976437
  • scopus:84907855678
ISSN
1651-2227
DOI
10.1111/apa.12729
language
English
LU publication?
yes
id
4ea52666-f8d5-46d5-9e2b-43d51c0b9a22 (old id 4796314)
date added to LUP
2016-04-01 12:59:57
date last changed
2022-03-13 21:33:31
@article{4ea52666-f8d5-46d5-9e2b-43d51c0b9a22,
  abstract     = {{AimChildhood obesity is now an established public health problem in most developed countries, and there is concern about a parallel increase of type 2 diabetes. The aim of this study was to estimate the prevalence of undiagnosed type 2 diabetes in overweight Swedish school children from 11 to 13years of age. MethodsBody mass index (BMI) was measured in 5528 schoolchildren in the 6th grade, from 11 to 13years of age, in five different regions in Sweden. Overweight was defined by international age- and sex-specific BMI cut-offs, corresponding to adult BMI cut-offs of 25kg/m(2) at 18years of age (ISO-BMI 25, n=1275). Haemoglobin A1c (HbA1c) was measured in 1126 children with ISO-BMI 25. Children with a Diabetes Control and Complications Trial aligned HbA1c 6.1% on two occasions underwent an oral glucose tolerance test (OGTT) to establish the diabetes diagnosis. ResultsOf 1126 children with ISO-BMI 25, 24 (2.1%) had at least one HbA1c value 6.1%. Three of them had HbA1c 6.1% on two occasions, and all of them had a normal OGTT. ConclusionIn this cross-sectional, population-based screening study of a high-risk group of 11- to 13-year-old Swedish school children, we found no indication of undiagnosed diabetes or impaired glucose tolerance.}},
  author       = {{Berhan, Yonas T. and Mollsten, Anna and Carlsson, Annelie and Hogberg, Lotta and Ivarsson, Anneli and Dahlquist, Gisela}},
  issn         = {{1651-2227}},
  keywords     = {{Childhood obesity; Diabetes mellitus type 2; Epidemiology}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{1078--1082}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Pædiatrica}},
  title        = {{Five-region study finds no evidence of undiagnosed type 2 diabetes in Swedish 11- to 13-year-olds}},
  url          = {{http://dx.doi.org/10.1111/apa.12729}},
  doi          = {{10.1111/apa.12729}},
  volume       = {{103}},
  year         = {{2014}},
}