Deep Eutectic Solvent Mediated Alkyne-Carbonyl Metathesis (ACM) Reaction for the Synthesis of 2H-Chromene Derivatives
(2019) In ChemistrySelect 4(20). p.6245-6249- Abstract
2H-Chromene is an important structural motif present in many biologically active compounds, natural products and showed many other properties. Deep Eutectic Solvent (DES) an environmentally benign and alternative to the conventional organic volatile solvents has been utilized first time for the synthesis of the 2H-chromene derivatives in moderated to excellent yields. The DES is recycled for 5 times for the synthesis of 2H-chromene derivatives. Based on the stability of ring size, we justified the regio-selectivity on the formation of cyclization product. Based on the control experiments, we ruled out the free radical mechanism and propose the ACM mechanistic path to construct chromene skeleton.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/47e0e5d5-3ad7-448a-a786-a6e42ec6e52d
- author
- Annes, Sesuraj Babiola ; Vigneshwar, Kulandaiappan ; Nivedha, Kolanchinathan ; Manojveer, Seetharaman LU and Ramesh, Subburethinam
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 2H-Chromene, 6-Exo-dig, ACM reaction, Deep Eutectic Solvent
- in
- ChemistrySelect
- volume
- 4
- issue
- 20
- pages
- 5 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85066469507
- ISSN
- 2365-6549
- DOI
- 10.1002/slct.201901350
- language
- English
- LU publication?
- yes
- id
- 47e0e5d5-3ad7-448a-a786-a6e42ec6e52d
- date added to LUP
- 2019-07-04 10:19:23
- date last changed
- 2022-04-26 02:54:26
@article{47e0e5d5-3ad7-448a-a786-a6e42ec6e52d, abstract = {{<p>2H-Chromene is an important structural motif present in many biologically active compounds, natural products and showed many other properties. Deep Eutectic Solvent (DES) an environmentally benign and alternative to the conventional organic volatile solvents has been utilized first time for the synthesis of the 2H-chromene derivatives in moderated to excellent yields. The DES is recycled for 5 times for the synthesis of 2H-chromene derivatives. Based on the stability of ring size, we justified the regio-selectivity on the formation of cyclization product. Based on the control experiments, we ruled out the free radical mechanism and propose the ACM mechanistic path to construct chromene skeleton.</p>}}, author = {{Annes, Sesuraj Babiola and Vigneshwar, Kulandaiappan and Nivedha, Kolanchinathan and Manojveer, Seetharaman and Ramesh, Subburethinam}}, issn = {{2365-6549}}, keywords = {{2H-Chromene; 6-Exo-dig; ACM reaction; Deep Eutectic Solvent}}, language = {{eng}}, number = {{20}}, pages = {{6245--6249}}, publisher = {{Wiley-Blackwell}}, series = {{ChemistrySelect}}, title = {{Deep Eutectic Solvent Mediated Alkyne-Carbonyl Metathesis (ACM) Reaction for the Synthesis of 2H-Chromene Derivatives}}, url = {{http://dx.doi.org/10.1002/slct.201901350}}, doi = {{10.1002/slct.201901350}}, volume = {{4}}, year = {{2019}}, }