Progress update from the hippocampal subfields group
Olsen, Rosanna K. ; Berron, David LU and Wisse, Laura E.M. LU
(2019)
In Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
11.
p.439-449
- Abstract
INTRODUCTION: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence.
METHODS: Our international working group, funded by the EU Joint Programme-Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption.
RESULTS: This progress report describes the initial... (More)
INTRODUCTION: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence.
METHODS: Our international working group, funded by the EU Joint Programme-Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption.
RESULTS: This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures.
DISCUSSION: A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.
(Less)
- author
- Olsen, Rosanna K.
; Berron, David
LU
and Wisse, Laura E.M.
LU
- author collaboration
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cytoarchitecture, ex vivo, Hippocampus, Histology, Human, Neuroanatomy, Neuroimaging, Structural imaging, Volumetry
- in
- Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
- volume
- 11
- pages
- 11 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:85066990984
- pmid:31245529
- ISSN
- 2352-8729
- DOI
- 10.1016/j.dadm.2019.04.001
- language
- English
- LU publication?
- yes
- id
- 47e4b803-2074-4ffc-b2aa-c53b3a950c5f
- date added to LUP
- 2019-06-26 10:30:15
- date last changed
- 2024-03-03 15:26:58
@article{47e4b803-2074-4ffc-b2aa-c53b3a950c5f,
abstract = {{<p>INTRODUCTION: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence.</p><p>METHODS: Our international working group, funded by the EU Joint Programme-Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption.</p><p>RESULTS: This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures.</p><p>DISCUSSION: A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.</p>}},
author = {{Olsen, Rosanna K. and Berron, David and Wisse, Laura E.M.}},
issn = {{2352-8729}},
keywords = {{Cytoarchitecture; ex vivo; Hippocampus; Histology; Human; Neuroanatomy; Neuroimaging; Structural imaging; Volumetry}},
language = {{eng}},
pages = {{439--449}},
publisher = {{Elsevier}},
series = {{Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring}},
title = {{Progress update from the hippocampal subfields group}},
url = {{http://dx.doi.org/10.1016/j.dadm.2019.04.001}},
doi = {{10.1016/j.dadm.2019.04.001}},
volume = {{11}},
year = {{2019}},
}