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Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation.

Kaufman, Bella; Shapira-Frommer, Ronnie; Schmutzler, Rita K; Audeh, M William; Friedlander, Michael; Balmaña, Judith; Mitchell, Gillian; Fried, Georgeta; Stemmer, Salomon M and Hubert, Ayala, et al. (2015) In Journal of Clinical Oncology 33(3). p.134-244
Abstract
Olaparib is an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2) -associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum of BRCA1/2-associated cancers.
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type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Oncology
volume
33
issue
3
pages
134 - 244
publisher
American Society of Clinical Oncology
external identifiers
  • pmid:25366685
  • wos:000352421400008
  • scopus:84921771510
ISSN
1527-7755
DOI
10.1200/JCO.2014.56.2728
language
English
LU publication?
yes
id
33800f58-da88-435a-8098-ae1b7e7aa410 (old id 4820289)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25366685?dopt=Abstract
date added to LUP
2014-12-01 18:56:04
date last changed
2017-11-19 03:19:39
@article{33800f58-da88-435a-8098-ae1b7e7aa410,
  abstract     = {Olaparib is an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2) -associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum of BRCA1/2-associated cancers.},
  author       = {Kaufman, Bella and Shapira-Frommer, Ronnie and Schmutzler, Rita K and Audeh, M William and Friedlander, Michael and Balmaña, Judith and Mitchell, Gillian and Fried, Georgeta and Stemmer, Salomon M and Hubert, Ayala and Rosengarten, Ora and Steiner, Mariana and Loman, Niklas and Bowen, Karin and Fielding, Anitra and Domchek, Susan M},
  issn         = {1527-7755},
  language     = {eng},
  number       = {3},
  pages        = {134--244},
  publisher    = {American Society of Clinical Oncology},
  series       = {Journal of Clinical Oncology},
  title        = {Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation.},
  url          = {http://dx.doi.org/10.1200/JCO.2014.56.2728},
  volume       = {33},
  year         = {2015},
}