The National Prevalence of Clinically Diagnosed Psoriatic Arthritis in Sweden in 2017
(2023) In The Journal of rheumatology 50(6). p.781-788- Abstract
Objective. Psoriatic arthritis (PsA) prevalence estimates vary across studies; studies based on national data are few. We aimed to estimate the prevalence of clinically diagnosed PsA in Sweden in 2017, overall and stratified by sex, age, education, and geography, and to quantify disease-modifying antirheumatic drug (DMARD) use among those in contact with specialized rheumatology care between 2015 and 2017. Methods. Individuals who were 18 to 79 years of age, alive and residing in Sweden on December 31, 2017, and had a prior PsA diagnosis were identified from the National Patient Register (NPR) and/or the Swedish Rheumatology Quality Register (SRQ). PsA prevalence was estimated according to a base case (BC) definition (ie, ≥ 1 main PsA... (More)
Objective. Psoriatic arthritis (PsA) prevalence estimates vary across studies; studies based on national data are few. We aimed to estimate the prevalence of clinically diagnosed PsA in Sweden in 2017, overall and stratified by sex, age, education, and geography, and to quantify disease-modifying antirheumatic drug (DMARD) use among those in contact with specialized rheumatology care between 2015 and 2017. Methods. Individuals who were 18 to 79 years of age, alive and residing in Sweden on December 31, 2017, and had a prior PsA diagnosis were identified from the National Patient Register (NPR) and/or the Swedish Rheumatology Quality Register (SRQ). PsA prevalence was estimated according to a base case (BC) definition (ie, ≥ 1 main PsA International Classification of Diseases code from rheumatology or internal medicine departments in the NPR or a PsA diagnosis in the SRQ), according to 4 sensitivity analysis definitions, and for those seen in specialized rheumatology care between 2015 and 2017. In the latter group, DMARD use during 2017 was also assessed. Data for stratifications were retrieved from national registers. Results. The crude national prevalence of PsA for adults, aged 18 to 79 years, was estimated at 0.39%, according to the BC definition; 0.34% after accounting for diagnostic misclassification; and 0.32% to 0.50% across all sensitivity analyses. The prevalence was lower in males and in those with a higher level of education. The prevalence for those seen in specialized rheumatology care between 2015 and 2017 was estimated at 0.24%. During 2017, 32% of patients in this population received biologic or targeted synthetic DMARDs, and 41% received conventional synthetic DMARDs only. Conclusion. The prevalence of clinically diagnosed PsA in adults, aged 18 to 79 years, in Sweden in 2017 was around 0.35%. Among PsA cases in recent contact with specialized rheumatology care, almost three-fourths received DMARD therapy in 2017.
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- author
- Exarchou, Sofia LU ; Wallman, Johan K. LU ; Di Giuseppe, Daniela ; Klingberg, Eva ; Sigurdardottir, Valgerdur ; Wedrén, Sara ; Lindström, Ulf ; Turesson, Carl LU ; Jacobsson, Lennart T.H. LU and Askling, Johan
- organization
- publishing date
- 2023-03-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- DMARD, epidemiology, prevalence, psoriatic arthritis, Sweden
- in
- The Journal of rheumatology
- volume
- 50
- issue
- 6
- pages
- 8 pages
- publisher
- Journal of Rheumatology Publishing Company Limited
- external identifiers
-
- scopus:85160968986
- pmid:36858434
- ISSN
- 0315-162X
- DOI
- 10.3899/jrheum.221139
- language
- English
- LU publication?
- yes
- id
- 483726a1-1f7f-4e55-806f-6b31105155d2
- date added to LUP
- 2023-03-07 14:19:27
- date last changed
- 2024-04-20 02:35:49
@article{483726a1-1f7f-4e55-806f-6b31105155d2,
abstract = {{<p>Objective. Psoriatic arthritis (PsA) prevalence estimates vary across studies; studies based on national data are few. We aimed to estimate the prevalence of clinically diagnosed PsA in Sweden in 2017, overall and stratified by sex, age, education, and geography, and to quantify disease-modifying antirheumatic drug (DMARD) use among those in contact with specialized rheumatology care between 2015 and 2017. Methods. Individuals who were 18 to 79 years of age, alive and residing in Sweden on December 31, 2017, and had a prior PsA diagnosis were identified from the National Patient Register (NPR) and/or the Swedish Rheumatology Quality Register (SRQ). PsA prevalence was estimated according to a base case (BC) definition (ie, ≥ 1 main PsA International Classification of Diseases code from rheumatology or internal medicine departments in the NPR or a PsA diagnosis in the SRQ), according to 4 sensitivity analysis definitions, and for those seen in specialized rheumatology care between 2015 and 2017. In the latter group, DMARD use during 2017 was also assessed. Data for stratifications were retrieved from national registers. Results. The crude national prevalence of PsA for adults, aged 18 to 79 years, was estimated at 0.39%, according to the BC definition; 0.34% after accounting for diagnostic misclassification; and 0.32% to 0.50% across all sensitivity analyses. The prevalence was lower in males and in those with a higher level of education. The prevalence for those seen in specialized rheumatology care between 2015 and 2017 was estimated at 0.24%. During 2017, 32% of patients in this population received biologic or targeted synthetic DMARDs, and 41% received conventional synthetic DMARDs only. Conclusion. The prevalence of clinically diagnosed PsA in adults, aged 18 to 79 years, in Sweden in 2017 was around 0.35%. Among PsA cases in recent contact with specialized rheumatology care, almost three-fourths received DMARD therapy in 2017.</p>}},
author = {{Exarchou, Sofia and Wallman, Johan K. and Di Giuseppe, Daniela and Klingberg, Eva and Sigurdardottir, Valgerdur and Wedrén, Sara and Lindström, Ulf and Turesson, Carl and Jacobsson, Lennart T.H. and Askling, Johan}},
issn = {{0315-162X}},
keywords = {{DMARD; epidemiology; prevalence; psoriatic arthritis; Sweden}},
language = {{eng}},
month = {{03}},
number = {{6}},
pages = {{781--788}},
publisher = {{Journal of Rheumatology Publishing Company Limited}},
series = {{The Journal of rheumatology}},
title = {{The National Prevalence of Clinically Diagnosed Psoriatic Arthritis in Sweden in 2017}},
url = {{http://dx.doi.org/10.3899/jrheum.221139}},
doi = {{10.3899/jrheum.221139}},
volume = {{50}},
year = {{2023}},
}