Rat alpha 1-microglobulin : co-expression in liver with the light chain of inter-alpha-trypsin inhibitor
(1992) In Biochimica et Biophysica Acta 1130(1). p.7-63- Abstract
A 1162 bp rat liver cDNA clone encoding the immunoregulatory plasma protein alpha 1-microglobulin was isolated and sequenced. The open reading frame encoded a 349 amino acid polyprotein, including alpha 1-microglobulin, 182 amino acids, and bikunin, the light chain of the plasma protein inter-alpha-trypsin inhibitor, 145 amino acids. The alpha 1-microglobulin/bikunin mRNA was found only in the liver when different tissues were examined. Free alpha 1-microglobulin and a polyprotein, containing both alpha 1-microglobulin and inter-alpha-trypsin inhibitor epitopes, were found in the microsomal fraction from rat liver homogenates.
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https://lup.lub.lu.se/record/48606fca-ffe1-45c8-befc-4e170afa0215
- author
- Lindqvist, A LU ; Bratt, T ; Altieri, M ; Kastern, W and Akerström, B LU
- organization
- publishing date
- 1992-02-28
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Alpha-Globulins/chemistry, Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, Glycoproteins/chemistry, Liver/metabolism, Membrane Glycoproteins, Molecular Sequence Data, Protein Precursors/chemistry, RNA, Messenger/genetics, Rats, Rats, Inbred Strains, Trypsin Inhibitor, Kunitz Soybean
- in
- Biochimica et Biophysica Acta
- volume
- 1130
- issue
- 1
- pages
- 7 - 63
- publisher
- Elsevier
- external identifiers
-
- pmid:1371936
- scopus:0026543131
- ISSN
- 0006-3002
- DOI
- 10.1016/0167-4781(92)90462-9
- language
- English
- LU publication?
- yes
- id
- 48606fca-ffe1-45c8-befc-4e170afa0215
- date added to LUP
- 2019-05-22 10:24:49
- date last changed
- 2024-06-26 17:36:49
@article{48606fca-ffe1-45c8-befc-4e170afa0215, abstract = {{<p>A 1162 bp rat liver cDNA clone encoding the immunoregulatory plasma protein alpha 1-microglobulin was isolated and sequenced. The open reading frame encoded a 349 amino acid polyprotein, including alpha 1-microglobulin, 182 amino acids, and bikunin, the light chain of the plasma protein inter-alpha-trypsin inhibitor, 145 amino acids. The alpha 1-microglobulin/bikunin mRNA was found only in the liver when different tissues were examined. Free alpha 1-microglobulin and a polyprotein, containing both alpha 1-microglobulin and inter-alpha-trypsin inhibitor epitopes, were found in the microsomal fraction from rat liver homogenates.</p>}}, author = {{Lindqvist, A and Bratt, T and Altieri, M and Kastern, W and Akerström, B}}, issn = {{0006-3002}}, keywords = {{Alpha-Globulins/chemistry; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Glycoproteins/chemistry; Liver/metabolism; Membrane Glycoproteins; Molecular Sequence Data; Protein Precursors/chemistry; RNA, Messenger/genetics; Rats; Rats, Inbred Strains; Trypsin Inhibitor, Kunitz Soybean}}, language = {{eng}}, month = {{02}}, number = {{1}}, pages = {{7--63}}, publisher = {{Elsevier}}, series = {{Biochimica et Biophysica Acta}}, title = {{Rat alpha 1-microglobulin : co-expression in liver with the light chain of inter-alpha-trypsin inhibitor}}, url = {{http://dx.doi.org/10.1016/0167-4781(92)90462-9}}, doi = {{10.1016/0167-4781(92)90462-9}}, volume = {{1130}}, year = {{1992}}, }