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Is the PANSS cognitive scale measuring cognition?

Nielsen, Rene Ernst; Lindstrom, Eva; Telleus, Gry Kjaersdam and Levander, Sten LU (2014) In Nordic Journal of Psychiatry 68(8). p.573-578
Abstract
Objective: To investigate the association between the Positive and Negative Syndrome Scale (PANSS) cognitive factors and cognition assessed by neuropsychological tests. Method: Ninety patients with a psychotic illness, the majority having a schizophrenia diagnosis, were assessed with PANSS ratings and tested by a comprehensive computerized neuropsychological test battery, EuCog. Results: Test performance was in the normal range for some of the cognitive indices, but substantially reduced for others, compared with norms, particularly speed-based indices. PANSS ratings were non-specifically associated with cognitive indices representing performance (speed and accuracy) and problem solving strategies (executive functions). There was no... (More)
Objective: To investigate the association between the Positive and Negative Syndrome Scale (PANSS) cognitive factors and cognition assessed by neuropsychological tests. Method: Ninety patients with a psychotic illness, the majority having a schizophrenia diagnosis, were assessed with PANSS ratings and tested by a comprehensive computerized neuropsychological test battery, EuCog. Results: Test performance was in the normal range for some of the cognitive indices, but substantially reduced for others, compared with norms, particularly speed-based indices. PANSS ratings were non-specifically associated with cognitive indices representing performance (speed and accuracy) and problem solving strategies (executive functions). There was no discriminant validity for the cognitive factor. A regression analysis suggested that the PANSS cognitive factors reflected verbal IQ but no other cognitive domain like memory, attention or speed. Conclusion: Cognitive test performance is associated with psychopathology as assessed by PANSS items but in a non-specific way. The PANSS cognitive subscale seems to reflect over-learned verbal skills rather than the cognitive domains, which are known to be specifically affected in schizophrenia and relevant for the prognosis. Consequently, PANSS ratings cannot replace the information inherent in neuropsychological test data. The extensive speed problem of patients with schizophrenia should be studied in more detail using test batteries that focus on that problem. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cognition, Neuropsychology, Schizophrenia
in
Nordic Journal of Psychiatry
volume
68
issue
8
pages
573 - 578
publisher
Informa Healthcare
external identifiers
  • wos:000343980600008
  • scopus:84911996103
ISSN
1502-4725
DOI
10.3109/08039488.2014.898790
language
English
LU publication?
yes
id
19519a85-4db8-48f3-aa45-74f66ee697a9 (old id 4875128)
date added to LUP
2015-01-07 10:26:41
date last changed
2017-01-01 04:18:21
@article{19519a85-4db8-48f3-aa45-74f66ee697a9,
  abstract     = {Objective: To investigate the association between the Positive and Negative Syndrome Scale (PANSS) cognitive factors and cognition assessed by neuropsychological tests. Method: Ninety patients with a psychotic illness, the majority having a schizophrenia diagnosis, were assessed with PANSS ratings and tested by a comprehensive computerized neuropsychological test battery, EuCog. Results: Test performance was in the normal range for some of the cognitive indices, but substantially reduced for others, compared with norms, particularly speed-based indices. PANSS ratings were non-specifically associated with cognitive indices representing performance (speed and accuracy) and problem solving strategies (executive functions). There was no discriminant validity for the cognitive factor. A regression analysis suggested that the PANSS cognitive factors reflected verbal IQ but no other cognitive domain like memory, attention or speed. Conclusion: Cognitive test performance is associated with psychopathology as assessed by PANSS items but in a non-specific way. The PANSS cognitive subscale seems to reflect over-learned verbal skills rather than the cognitive domains, which are known to be specifically affected in schizophrenia and relevant for the prognosis. Consequently, PANSS ratings cannot replace the information inherent in neuropsychological test data. The extensive speed problem of patients with schizophrenia should be studied in more detail using test batteries that focus on that problem.},
  author       = {Nielsen, Rene Ernst and Lindstrom, Eva and Telleus, Gry Kjaersdam and Levander, Sten},
  issn         = {1502-4725},
  keyword      = {Cognition,Neuropsychology,Schizophrenia},
  language     = {eng},
  number       = {8},
  pages        = {573--578},
  publisher    = {Informa Healthcare},
  series       = {Nordic Journal of Psychiatry},
  title        = {Is the PANSS cognitive scale measuring cognition?},
  url          = {http://dx.doi.org/10.3109/08039488.2014.898790},
  volume       = {68},
  year         = {2014},
}