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Gestational diabetes mellitus among Nordic Caucasian women: Prevalence and risk factors according to WHO and simplified IADPSG criteria

Helseth, Ragnhild; Salvesen, Oyvind; Stafne, Signe N.; Morkved, Siv; Salvesen, Kjell LU and Carlsen, Sven M. (2014) In Scandinavian Journal of Clinical & Laboratory Investigation 74(7). p.620-628
Abstract
Background. Gestational diabetes mellitus (GDM) is associated with both maternal and offspring adverse effects. The World Health Organization (WHO) has recently adopted novel GDM criteria. The aim of this study was to evaluate the former WHO and a simplified version of the new International Association for Diabetes in Pregnancy Study Group (IADPSG) criteria as to prevalence of and risk factors for GDM in a Nordic Caucasian population. Methods. A 75 g oral glucose tolerance test was performed in 687 women at 18-22 and 32-36 pregnancy weeks. GDM was defined according to the WHO criteria as fasting plasma glucose >= 7.0 mmol/L and/or 2-hour plasma glucose >= 7.8 mmol/L and by a simplified version of the IADPSG criteria as either fasting... (More)
Background. Gestational diabetes mellitus (GDM) is associated with both maternal and offspring adverse effects. The World Health Organization (WHO) has recently adopted novel GDM criteria. The aim of this study was to evaluate the former WHO and a simplified version of the new International Association for Diabetes in Pregnancy Study Group (IADPSG) criteria as to prevalence of and risk factors for GDM in a Nordic Caucasian population. Methods. A 75 g oral glucose tolerance test was performed in 687 women at 18-22 and 32-36 pregnancy weeks. GDM was defined according to the WHO criteria as fasting plasma glucose >= 7.0 mmol/L and/or 2-hour plasma glucose >= 7.8 mmol/L and by a simplified version of the IADPSG criteria as either fasting glucose >= 5.1 mmol/L and/or 2-h plasma glucose >= 8.5 mmol/L. One-hour glucose values were not available and were thus not included in the diagnosis of GDM by IADPSG. Prevalence of GDM during pregnancy and risk factors for GDM at 18-22 weeks were studied in retrospect according to each of the two criteria. Results. The total prevalence of GDM during pregnancy was 6.1% (42/687) for the WHO criteria and 7.4% (51/687) for the simplified IADPSG criteria. High maternal age and short stature were independently associated with WHO GDM. Maternal age, fasting insulin and no regular exercise at 18-22 pregnancy weeks associated with simplified IADPSG GDM. Conclusions. Simplified IADPSG criteria moderately increase GDM prevalence compared with the WHO criteria. Risk factors for GDM differ with the diagnostic criteria used. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
GDM, GDM diagnostic criteria, GDM risk factors, IADPSG criteria, pregnancy-induced diabetes, WHO criteria
in
Scandinavian Journal of Clinical & Laboratory Investigation
volume
74
issue
7
pages
620 - 628
publisher
Informa Healthcare
external identifiers
  • wos:000343756500010
  • scopus:84911925918
ISSN
1502-7686
DOI
10.3109/00365513.2014.928942
language
English
LU publication?
yes
id
7fbc4b15-3f19-44d7-b5f0-f2d0950cba5e (old id 4879070)
date added to LUP
2014-12-22 11:58:11
date last changed
2017-09-17 06:51:45
@article{7fbc4b15-3f19-44d7-b5f0-f2d0950cba5e,
  abstract     = {Background. Gestational diabetes mellitus (GDM) is associated with both maternal and offspring adverse effects. The World Health Organization (WHO) has recently adopted novel GDM criteria. The aim of this study was to evaluate the former WHO and a simplified version of the new International Association for Diabetes in Pregnancy Study Group (IADPSG) criteria as to prevalence of and risk factors for GDM in a Nordic Caucasian population. Methods. A 75 g oral glucose tolerance test was performed in 687 women at 18-22 and 32-36 pregnancy weeks. GDM was defined according to the WHO criteria as fasting plasma glucose >= 7.0 mmol/L and/or 2-hour plasma glucose >= 7.8 mmol/L and by a simplified version of the IADPSG criteria as either fasting glucose >= 5.1 mmol/L and/or 2-h plasma glucose >= 8.5 mmol/L. One-hour glucose values were not available and were thus not included in the diagnosis of GDM by IADPSG. Prevalence of GDM during pregnancy and risk factors for GDM at 18-22 weeks were studied in retrospect according to each of the two criteria. Results. The total prevalence of GDM during pregnancy was 6.1% (42/687) for the WHO criteria and 7.4% (51/687) for the simplified IADPSG criteria. High maternal age and short stature were independently associated with WHO GDM. Maternal age, fasting insulin and no regular exercise at 18-22 pregnancy weeks associated with simplified IADPSG GDM. Conclusions. Simplified IADPSG criteria moderately increase GDM prevalence compared with the WHO criteria. Risk factors for GDM differ with the diagnostic criteria used.},
  author       = {Helseth, Ragnhild and Salvesen, Oyvind and Stafne, Signe N. and Morkved, Siv and Salvesen, Kjell and Carlsen, Sven M.},
  issn         = {1502-7686},
  keyword      = {GDM,GDM diagnostic criteria,GDM risk factors,IADPSG criteria,pregnancy-induced diabetes,WHO criteria},
  language     = {eng},
  number       = {7},
  pages        = {620--628},
  publisher    = {Informa Healthcare},
  series       = {Scandinavian Journal of Clinical & Laboratory Investigation},
  title        = {Gestational diabetes mellitus among Nordic Caucasian women: Prevalence and risk factors according to WHO and simplified IADPSG criteria},
  url          = {http://dx.doi.org/10.3109/00365513.2014.928942},
  volume       = {74},
  year         = {2014},
}