Indications, Detection, Completion and Retention Rates of Capsule Endoscopy in Two Decades of Use : A Systematic Review and Meta-Analysis
(2022) In Diagnostics 12(5).- Abstract
Background: Capsule endoscopy (CE) has become a widespread modality for non-invasive evaluation of the gastrointestinal (GI) tract, with several CE models having been developed throughout the years. The aim of this systematic review and meta-analysis is to evaluate performance measures such as completion, detection and retention rates of CE. Methods: Literature through to August 2021 was screened for articles regarding all capsule types: small bowel, double-headed capsule for the colon or PillCam® Crohn’s capsule, magnetically-controlled capsule endoscopy, esophageal capsule and patency capsule. Primary outcomes included detection rate (DR), completion rate (CR) and capsule retention rate (RR). DR, CR and RR were also analyzed in... (More)
Background: Capsule endoscopy (CE) has become a widespread modality for non-invasive evaluation of the gastrointestinal (GI) tract, with several CE models having been developed throughout the years. The aim of this systematic review and meta-analysis is to evaluate performance measures such as completion, detection and retention rates of CE. Methods: Literature through to August 2021 was screened for articles regarding all capsule types: small bowel, double-headed capsule for the colon or PillCam® Crohn’s capsule, magnetically-controlled capsule endoscopy, esophageal capsule and patency capsule. Primary outcomes included detection rate (DR), completion rate (CR) and capsule retention rate (RR). DR, CR and RR were also analyzed in relation to indications such as obscure GI bleeding (OGIB), known/suspected Crohn’s disease (CD), celiac disease (CeD), neoplastic lesions (NL) and clinical symptoms (CS). Results: 328 original articles involving 86,930 patients who underwent CE were included. OGIB was the most common indication (n = 44,750), followed by CS (n = 17,897), CD (n = 11,299), NL (n = 4989) and CeD (n = 947). The most used capsule type was small bowel CE in 236 studies. DR, CR and RR for all indications were 59%, 89.6% and 2%, respectively. According to specific indications: DR were 55%, 66%, 63%, 52% and 62%; CR were 90.6%, 86.5%, 78.2%, 94% and 92.8%; and RR were 2%, 4%, 1%, 6% and 2%. Conclusions: Pooled DR, CR and RR are acceptable for all capsule types. OGIB is the most common indication for CE. Technological advancements have expanded the scope of CE devices in detecting GI pathology with acceptable rates for a complete examination.
(Less)
- author
- organization
- publishing date
- 2022-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- capsule endoscopy, completion, detection, indications, systematic review
- in
- Diagnostics
- volume
- 12
- issue
- 5
- article number
- 1105
- publisher
- MDPI AG
- external identifiers
-
- pmid:35626261
- scopus:85129737069
- ISSN
- 2075-4418
- DOI
- 10.3390/diagnostics12051105
- language
- English
- LU publication?
- yes
- id
- 48928219-2ced-4fbd-8bfe-df48f49707eb
- date added to LUP
- 2023-01-04 13:13:32
- date last changed
- 2024-04-18 18:21:12
@article{48928219-2ced-4fbd-8bfe-df48f49707eb,
abstract = {{<p>Background: Capsule endoscopy (CE) has become a widespread modality for non-invasive evaluation of the gastrointestinal (GI) tract, with several CE models having been developed throughout the years. The aim of this systematic review and meta-analysis is to evaluate performance measures such as completion, detection and retention rates of CE. Methods: Literature through to August 2021 was screened for articles regarding all capsule types: small bowel, double-headed capsule for the colon or PillCam® Crohn’s capsule, magnetically-controlled capsule endoscopy, esophageal capsule and patency capsule. Primary outcomes included detection rate (DR), completion rate (CR) and capsule retention rate (RR). DR, CR and RR were also analyzed in relation to indications such as obscure GI bleeding (OGIB), known/suspected Crohn’s disease (CD), celiac disease (CeD), neoplastic lesions (NL) and clinical symptoms (CS). Results: 328 original articles involving 86,930 patients who underwent CE were included. OGIB was the most common indication (n = 44,750), followed by CS (n = 17,897), CD (n = 11,299), NL (n = 4989) and CeD (n = 947). The most used capsule type was small bowel CE in 236 studies. DR, CR and RR for all indications were 59%, 89.6% and 2%, respectively. According to specific indications: DR were 55%, 66%, 63%, 52% and 62%; CR were 90.6%, 86.5%, 78.2%, 94% and 92.8%; and RR were 2%, 4%, 1%, 6% and 2%. Conclusions: Pooled DR, CR and RR are acceptable for all capsule types. OGIB is the most common indication for CE. Technological advancements have expanded the scope of CE devices in detecting GI pathology with acceptable rates for a complete examination.</p>}},
author = {{Valdivia, Pablo Cortegoso and Skonieczna-żydecka, Karolina and Elosua, Alfonso and Sciberras, Martina and Piccirelli, Stefania and Rullan, Maria and Tabone, Trevor and Gawel, Katarzyna and Stachowski, Adam and Lemiński, Artur and Marlicz, Wojciech and Fernández-Urién, Ignacio and Ellul, Pierre and Spada, Cristiano and Pennazio, Marco and Toth, Ervin and Koulaouzidis, Anastasios}},
issn = {{2075-4418}},
keywords = {{capsule endoscopy; completion; detection; indications; systematic review}},
language = {{eng}},
number = {{5}},
publisher = {{MDPI AG}},
series = {{Diagnostics}},
title = {{Indications, Detection, Completion and Retention Rates of Capsule Endoscopy in Two Decades of Use : A Systematic Review and Meta-Analysis}},
url = {{http://dx.doi.org/10.3390/diagnostics12051105}},
doi = {{10.3390/diagnostics12051105}},
volume = {{12}},
year = {{2022}},
}