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Swedish Experiences From Patch Testing Methylisothiazolinone Separately.

Engfeldt, Malin LU ; Bråred-Christensson, Johanna; Isaksson, Marléne LU ; Matura, Mihály; Morgardt-Ryberg, Kristina LU ; Stenberg, Berndt; Svedman, Cecilia LU and Bruze, Magnus LU (2015) In Acta Dermato-Venereologica 95(6). p.717-719
Abstract
The preservative methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is a well-known sensitiser and present in the Swedish baseline series since the 1980s. The proportions of MCI/MI are 3:1. MI alone has been used as a preservative since less than 10 years. This study was conducted on behalf of the Swedish Contact Dermatitis Research Group to evaluate inclusion of MI in the Swedish baseline series since the preparation of MCI/MI might fail to detect contact-allergic reactions to MI alone. Patients with suspected allergic contact dermatitis at 5 Swedish dermatology departments were consecutively patch tested with MI 2,000 ppm aq and MCI/MI 200 ppm aq. The number of cases with exclusive contact allergy to MI varied between 0.8-4.2%.... (More)
The preservative methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is a well-known sensitiser and present in the Swedish baseline series since the 1980s. The proportions of MCI/MI are 3:1. MI alone has been used as a preservative since less than 10 years. This study was conducted on behalf of the Swedish Contact Dermatitis Research Group to evaluate inclusion of MI in the Swedish baseline series since the preparation of MCI/MI might fail to detect contact-allergic reactions to MI alone. Patients with suspected allergic contact dermatitis at 5 Swedish dermatology departments were consecutively patch tested with MI 2,000 ppm aq and MCI/MI 200 ppm aq. The number of cases with exclusive contact allergy to MI varied between 0.8-4.2%. In total, 1.9% reacted exclusively to MI and not to MCI/MI. Due to the considerable frequency of contact allergy to MI not traced by MCI/MI, MI 2,000 ppm aq is included in the Swedish baseline series from January 2014. This corresponds to a dose of 60 μg/cm2. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
95
issue
6
pages
717 - 719
publisher
Medical Journals Limited
external identifiers
  • pmid:25474255
  • wos:000359093800014
  • scopus:84932152066
ISSN
1651-2057
DOI
10.2340/00015555-2029
language
English
LU publication?
yes
id
fcc9a62a-9edb-4f8b-adfe-f17ef62586b8 (old id 4912720)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25474255?dopt=Abstract
date added to LUP
2015-01-08 19:47:16
date last changed
2017-07-09 03:06:29
@article{fcc9a62a-9edb-4f8b-adfe-f17ef62586b8,
  abstract     = {The preservative methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is a well-known sensitiser and present in the Swedish baseline series since the 1980s. The proportions of MCI/MI are 3:1. MI alone has been used as a preservative since less than 10 years. This study was conducted on behalf of the Swedish Contact Dermatitis Research Group to evaluate inclusion of MI in the Swedish baseline series since the preparation of MCI/MI might fail to detect contact-allergic reactions to MI alone. Patients with suspected allergic contact dermatitis at 5 Swedish dermatology departments were consecutively patch tested with MI 2,000 ppm aq and MCI/MI 200 ppm aq. The number of cases with exclusive contact allergy to MI varied between 0.8-4.2%. In total, 1.9% reacted exclusively to MI and not to MCI/MI. Due to the considerable frequency of contact allergy to MI not traced by MCI/MI, MI 2,000 ppm aq is included in the Swedish baseline series from January 2014. This corresponds to a dose of 60 μg/cm2.},
  author       = {Engfeldt, Malin and Bråred-Christensson, Johanna and Isaksson, Marléne and Matura, Mihály and Morgardt-Ryberg, Kristina and Stenberg, Berndt and Svedman, Cecilia and Bruze, Magnus},
  issn         = {1651-2057},
  language     = {eng},
  number       = {6},
  pages        = {717--719},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Swedish Experiences From Patch Testing Methylisothiazolinone Separately.},
  url          = {http://dx.doi.org/10.2340/00015555-2029},
  volume       = {95},
  year         = {2015},
}