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Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.

Uronis, Hope E; Ekström, Magnus LU ; Currow, David C; McCrory, Douglas C; Samsa, Gregory P and Abernethy, Amy P (2015) In Thorax 70(5). p.492-494
Abstract
We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I(2)=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Thorax
volume
70
issue
5
pages
492 - 494
publisher
BMJ Publishing Group
external identifiers
  • pmid:25472664
  • wos:000352846600020
  • scopus:84929459132
ISSN
1468-3296
DOI
10.1136/thoraxjnl-2014-205720
language
English
LU publication?
yes
id
0275e4b6-c003-4bf2-a4cd-ecd1aab3e33d (old id 4912739)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25472664?dopt=Abstract
date added to LUP
2015-01-08 19:50:14
date last changed
2017-08-27 03:08:54
@article{0275e4b6-c003-4bf2-a4cd-ecd1aab3e33d,
  abstract     = {We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I(2)=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.},
  author       = {Uronis, Hope E and Ekström, Magnus and Currow, David C and McCrory, Douglas C and Samsa, Gregory P and Abernethy, Amy P},
  issn         = {1468-3296},
  language     = {eng},
  number       = {5},
  pages        = {492--494},
  publisher    = {BMJ Publishing Group},
  series       = {Thorax},
  title        = {Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.},
  url          = {http://dx.doi.org/10.1136/thoraxjnl-2014-205720},
  volume       = {70},
  year         = {2015},
}