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Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.

Tivesten, Asa; Vandenput, Liesbeth; Carlzon, Daniel; Nilsson, Maria; Karlsson, Magnus LU ; Ljunggren, Osten; Barrett-Connor, Elizabeth; Mellström, Dan and Ohlsson, Claes (2014) In Journal of the American College of Cardiology 64(17). p.1801-1810
Abstract
The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abundant steroid hormone in human blood. Its levels decline dramatically with age. Despite the great amount of literature on vascular and metabolic actions of DHEA/-S, evidence for an association between DHEA/-S levels and cardiovascular events is contradictory.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of the American College of Cardiology
volume
64
issue
17
pages
1801 - 1810
publisher
Elsevier USA
external identifiers
  • wos:000344616600007
  • pmid:25443702
  • scopus:84908193694
ISSN
0735-1097
DOI
10.1016/j.jacc.2014.05.076
language
English
LU publication?
yes
id
99188fdc-dec0-4092-b8aa-aab872434fd5 (old id 4913449)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25443702?dopt=Abstract
date added to LUP
2015-01-06 10:53:28
date last changed
2017-08-06 03:07:32
@article{99188fdc-dec0-4092-b8aa-aab872434fd5,
  abstract     = {The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abundant steroid hormone in human blood. Its levels decline dramatically with age. Despite the great amount of literature on vascular and metabolic actions of DHEA/-S, evidence for an association between DHEA/-S levels and cardiovascular events is contradictory.},
  author       = {Tivesten, Asa and Vandenput, Liesbeth and Carlzon, Daniel and Nilsson, Maria and Karlsson, Magnus and Ljunggren, Osten and Barrett-Connor, Elizabeth and Mellström, Dan and Ohlsson, Claes},
  issn         = {0735-1097},
  language     = {eng},
  number       = {17},
  pages        = {1801--1810},
  publisher    = {Elsevier USA},
  series       = {Journal of the American College of Cardiology},
  title        = {Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.},
  url          = {http://dx.doi.org/10.1016/j.jacc.2014.05.076},
  volume       = {64},
  year         = {2014},
}