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Acceptance of covid-19 vaccination at different hypothetical efficacy and safety levels in ten countries in asia, africa, and south america

Rosiello, Dott F. ; Anwar, Samsul ; Yufika, Amanda ; Adam, Rashed Y. ; Ismaeil, Mohajer Ih ; Ismail, Asma Y. ; Dahman, Nesrine Bh ; Hafsi, Montacer ; Ferjani, Manel and Sami, Farah S. , et al. (2021) In Narra J 1(3).
Abstract

Vaccine hesitancy, defined as the reluctance or rejection in receiving a vaccine despite its availability, represents a major challenge to global health efforts aiming to control the ongoing COVID-19 pandemic. Understanding the possible factors correlated with COVID-19 vaccine hesitancy using a refined well-informed approach can be helpful to address the phenomenon. The current study aimed to evaluate COVID-19 vaccine acceptance rates using four hypothetical scenarios of varying levels of vaccine efficacy and safety profiles in ten Asian, African and South American countries. These scenarios included: 95% efficacy and 20% side effects (Vaccine A), 75% efficacy and 5% side effects (Vaccine B); 75% efficacy and 20% side effects (Vaccine... (More)

Vaccine hesitancy, defined as the reluctance or rejection in receiving a vaccine despite its availability, represents a major challenge to global health efforts aiming to control the ongoing COVID-19 pandemic. Understanding the possible factors correlated with COVID-19 vaccine hesitancy using a refined well-informed approach can be helpful to address the phenomenon. The current study aimed to evaluate COVID-19 vaccine acceptance rates using four hypothetical scenarios of varying levels of vaccine efficacy and safety profiles in ten Asian, African and South American countries. These scenarios included: 95% efficacy and 20% side effects (Vaccine A), 75% efficacy and 5% side effects (Vaccine B); 75% efficacy and 20% side effects (Vaccine C) and 50% efficacy and 5% side effects (Vaccine D). This study used a self-administered online survey that was distributed during February–May 2021. The total number of study respondents was 1337 with countries of residence as follows: India (21.1%), Pakistan (12.9%), Sudan (11.2%), Nigeria (9.3%), Iran (8.2%), Bangladesh and Brazil (7.9%), Chile (7.7%), Tunisia (7.6%), and Egypt (6.2%). The overall acceptance rates for COVID-19 vaccination were variable based on varying degrees of safety and efficacy as follows: 55.6% for Vaccine C, 58.3% for Vaccine D, 74.0% for Vaccine A and 80.1% for Vaccine B. The highest levels of COVID-19 vaccine acceptance were observed in Brazil followed by Chile across the four different safety and efficacy scenarios. The lowest COVID-19 vaccine acceptance rates were reported in Egypt and Tunisia for the low safety scenarios (20% side effects), and the low efficacy scenario (50% efficacy). The study revealed the potential effect of vaccine safety and efficacy on the intention to get COVID-19 vaccination. At the same efficacy level, higher possibility of side effects caused a large drop in COVID-19 vaccine acceptance rate. This indicates the importance of accurate communication regarding vaccine safety and efficacy on attitude towards the vaccine and intentions to get vaccinated. Regional differences in COVID-19 vaccine acceptance were observed with the Middle East/North African countries showing the lowest rates and the South American countries displaying the highest vaccine acceptance rates.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acceptance, COVID-19, COVID-19 vaccine, Hesitancy, WHO SAGE
in
Narra J
volume
1
issue
3
article number
e55
publisher
Narra Sains Indonesia
external identifiers
  • scopus:85121721702
ISSN
2807-2618
DOI
10.52225/narra.v1i3.55
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2021, School of Medicine, Universitas Syiah Kuala. All rights reserved.
id
4917b7bc-f2a9-47ab-9175-0facb6aef8aa
date added to LUP
2024-10-16 09:57:50
date last changed
2025-04-04 15:21:33
@article{4917b7bc-f2a9-47ab-9175-0facb6aef8aa,
  abstract     = {{<p>Vaccine hesitancy, defined as the reluctance or rejection in receiving a vaccine despite its availability, represents a major challenge to global health efforts aiming to control the ongoing COVID-19 pandemic. Understanding the possible factors correlated with COVID-19 vaccine hesitancy using a refined well-informed approach can be helpful to address the phenomenon. The current study aimed to evaluate COVID-19 vaccine acceptance rates using four hypothetical scenarios of varying levels of vaccine efficacy and safety profiles in ten Asian, African and South American countries. These scenarios included: 95% efficacy and 20% side effects (Vaccine A), 75% efficacy and 5% side effects (Vaccine B); 75% efficacy and 20% side effects (Vaccine C) and 50% efficacy and 5% side effects (Vaccine D). This study used a self-administered online survey that was distributed during February–May 2021. The total number of study respondents was 1337 with countries of residence as follows: India (21.1%), Pakistan (12.9%), Sudan (11.2%), Nigeria (9.3%), Iran (8.2%), Bangladesh and Brazil (7.9%), Chile (7.7%), Tunisia (7.6%), and Egypt (6.2%). The overall acceptance rates for COVID-19 vaccination were variable based on varying degrees of safety and efficacy as follows: 55.6% for Vaccine C, 58.3% for Vaccine D, 74.0% for Vaccine A and 80.1% for Vaccine B. The highest levels of COVID-19 vaccine acceptance were observed in Brazil followed by Chile across the four different safety and efficacy scenarios. The lowest COVID-19 vaccine acceptance rates were reported in Egypt and Tunisia for the low safety scenarios (20% side effects), and the low efficacy scenario (50% efficacy). The study revealed the potential effect of vaccine safety and efficacy on the intention to get COVID-19 vaccination. At the same efficacy level, higher possibility of side effects caused a large drop in COVID-19 vaccine acceptance rate. This indicates the importance of accurate communication regarding vaccine safety and efficacy on attitude towards the vaccine and intentions to get vaccinated. Regional differences in COVID-19 vaccine acceptance were observed with the Middle East/North African countries showing the lowest rates and the South American countries displaying the highest vaccine acceptance rates.</p>}},
  author       = {{Rosiello, Dott F. and Anwar, Samsul and Yufika, Amanda and Adam, Rashed Y. and Ismaeil, Mohajer Ih and Ismail, Asma Y. and Dahman, Nesrine Bh and Hafsi, Montacer and Ferjani, Manel and Sami, Farah S. and Monib, Fatma A. and Subramaniam, R. and Anandu, Sunil and Haque, Md Ariful and Ferreto, Lirane Ed and Aburto, José To and Rojas, Jorge Et and Enitan, Seyi S. and Yomi, Akele R. and Ezigbo, Eyiuche D. and Babadi, Elham and Kakemam, Edris and Malik, Najma I. and Ullah, Irfan and Sallam, Malik}},
  issn         = {{2807-2618}},
  keywords     = {{Acceptance; COVID-19; COVID-19 vaccine; Hesitancy; WHO SAGE}},
  language     = {{eng}},
  number       = {{3}},
  publisher    = {{Narra Sains Indonesia}},
  series       = {{Narra J}},
  title        = {{Acceptance of covid-19 vaccination at different hypothetical efficacy and safety levels in ten countries in asia, africa, and south america}},
  url          = {{http://dx.doi.org/10.52225/narra.v1i3.55}},
  doi          = {{10.52225/narra.v1i3.55}},
  volume       = {{1}},
  year         = {{2021}},
}