The P-Wave Time-Domain Significant Features to Evaluate Substrate Modification After Catheter Ablation of Paroxysmal Atrial Fibrillation
(2022) 2022 Computing in Cardiology, CinC 2022 In Computing in Cardiology 2022-September.- Abstract
The outcome of catheter ablation (CA) of atrial fibrillation (AF) is vastly analyzed by the entire P-wave duration (PWD). However, the first and second P-wave parts, corresponding to right (RA) and left atrial (LA) wavefront propagation, may be unequally modified. Five-minute lead II recordings before and after the first-ever CA of 40 parox-ysmal AF patients were analyzed and P-wave features were calculated: PWDon-off of the entire P-wave and each P-wave part (RA:PWDon-peak, LA:PWDpeak-off) and the time from P-wave onset or offset to the R-peak (PWDon-R and PWDoff-R, respectively). Heart-rate (HR) adjustment (HRA) mitigated the HR fluctuations. Prelpost-CA comparison was performed with Mann-Whitney U-test and median values were... (More)
The outcome of catheter ablation (CA) of atrial fibrillation (AF) is vastly analyzed by the entire P-wave duration (PWD). However, the first and second P-wave parts, corresponding to right (RA) and left atrial (LA) wavefront propagation, may be unequally modified. Five-minute lead II recordings before and after the first-ever CA of 40 parox-ysmal AF patients were analyzed and P-wave features were calculated: PWDon-off of the entire P-wave and each P-wave part (RA:PWDon-peak, LA:PWDpeak-off) and the time from P-wave onset or offset to the R-peak (PWDon-R and PWDoff-R, respectively). Heart-rate (HR) adjustment (HRA) mitigated the HR fluctuations. Prelpost-CA comparison was performed with Mann-Whitney U-test and median values were calculated. Pearson's correlation was calculated between PWD and the remaining features. The effect of CA with (Δ: -17.96%) or without HRA (Δ: -9.84%) was significant at the entire PWDon-off and at the PWDpeak-off(HRA:Δ: -27.77%, no HRA: Δ: -22.03%). PWDon-off showed a stronger correlation with RA than LA(ρmax=0.805 vs ρmax=0.541). P-wave features corresponding to RA are more strongly related to the entire P-wave. Nevertheless, only the P-wave part associated with LA is significantly affected by CA. That being so, studies are encouraged to incorporate part-time P-wave analysis.
(Less)
- author
- Vraka, Aikaterini ; Bertomeu-Gonzalcz, Vicente ; Sornmo, Leif LU ; Zangroniz, Roberto ; Alcaraz, Raul and Rieta, Jose J.
- organization
- publishing date
- 2022
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- 2022 Computing in Cardiology, CinC 2022
- series title
- Computing in Cardiology
- volume
- 2022-September
- publisher
- IEEE Computer Society
- conference name
- 2022 Computing in Cardiology, CinC 2022
- conference location
- Tampere, Finland
- conference dates
- 2022-09-04 - 2022-09-07
- external identifiers
-
- scopus:85152939851
- ISSN
- 2325-887X
- 2325-8861
- ISBN
- 9798350300970
- DOI
- 10.22489/CinC.2022.011
- language
- English
- LU publication?
- yes
- id
- 493df823-c447-4147-ae0e-595d15c2c349
- date added to LUP
- 2023-07-21 14:34:23
- date last changed
- 2024-04-05 21:32:11
@inproceedings{493df823-c447-4147-ae0e-595d15c2c349,
abstract = {{<p>The outcome of catheter ablation (CA) of atrial fibrillation (AF) is vastly analyzed by the entire P-wave duration (PWD). However, the first and second P-wave parts, corresponding to right (RA) and left atrial (LA) wavefront propagation, may be unequally modified. Five-minute lead II recordings before and after the first-ever CA of 40 parox-ysmal AF patients were analyzed and P-wave features were calculated: PWDon-off of the entire P-wave and each P-wave part (RA:PWDon-peak, LA:PWDpeak-off) and the time from P-wave onset or offset to the R-peak (PWDon-R and PWDoff-R, respectively). Heart-rate (HR) adjustment (HRA) mitigated the HR fluctuations. Prelpost-CA comparison was performed with Mann-Whitney U-test and median values were calculated. Pearson's correlation was calculated between PWD and the remaining features. The effect of CA with (Δ: -17.96%) or without HRA (Δ: -9.84%) was significant at the entire PWDon-off and at the PWDpeak-off(HRA:Δ: -27.77%, no HRA: Δ: -22.03%). PWDon-off showed a stronger correlation with RA than LA(ρmax=0.805 vs ρmax=0.541). P-wave features corresponding to RA are more strongly related to the entire P-wave. Nevertheless, only the P-wave part associated with LA is significantly affected by CA. That being so, studies are encouraged to incorporate part-time P-wave analysis.</p>}},
author = {{Vraka, Aikaterini and Bertomeu-Gonzalcz, Vicente and Sornmo, Leif and Zangroniz, Roberto and Alcaraz, Raul and Rieta, Jose J.}},
booktitle = {{2022 Computing in Cardiology, CinC 2022}},
isbn = {{9798350300970}},
issn = {{2325-887X}},
language = {{eng}},
publisher = {{IEEE Computer Society}},
series = {{Computing in Cardiology}},
title = {{The P-Wave Time-Domain Significant Features to Evaluate Substrate Modification After Catheter Ablation of Paroxysmal Atrial Fibrillation}},
url = {{http://dx.doi.org/10.22489/CinC.2022.011}},
doi = {{10.22489/CinC.2022.011}},
volume = {{2022-September}},
year = {{2022}},
}