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Burden of Skin and Subcutaneous Diseases in Iran and Neighboring Countries : Results from the Global Burden of Disease Study 2015

Karimkhani, Chante ; Dellavalle, Robert P. ; Karimi, Seyed M ; Rahimi-Movaghar, Vafa ; Pourmalek, Farshad ; Ahmad Kiadaliri, Aliasghar LU orcid ; Sahraian, Mohammad Ali ; Roshandel, Gholamreza ; Fereshtehnejad, Seyed-Mohammad and Qorbani, Mostafa , et al. (2017) In Archives of Iranian Medicine 20(7). p.429-440
Abstract

BACKGROUND: Iran and its neighboring countries represent four world regions with unique cultures and geography. Skin diseases span a wide diversity of etiologies including infectious, inflammatory, autoimmune, vascular, neurogenic, and oncologic. The Global Burden of Disease Study (GBD) 2015 measures the burden from skin diseases in 195 countries.

METHODS: Epidemiologic data were collected from literature review, survey data, and hospital inpatient/outpatient claims data. These raw data entered modeling using a Bayesian meta-regression tool, DisMod MR-2.1, which yielded prevalence estimates by age/sex/location/year. Prevalence estimates were combined with disability weights to yield years lived with disability (YLDs). YLDs are... (More)

BACKGROUND: Iran and its neighboring countries represent four world regions with unique cultures and geography. Skin diseases span a wide diversity of etiologies including infectious, inflammatory, autoimmune, vascular, neurogenic, and oncologic. The Global Burden of Disease Study (GBD) 2015 measures the burden from skin diseases in 195 countries.

METHODS: Epidemiologic data were collected from literature review, survey data, and hospital inpatient/outpatient claims data. These raw data entered modeling using a Bayesian meta-regression tool, DisMod MR-2.1, which yielded prevalence estimates by age/sex/location/year. Prevalence estimates were combined with disability weights to yield years lived with disability (YLDs). YLDs are combined with years of life lost (YLLs), from mortality estimates, to yield disability-adjusted life years (DALYs). DALYs were obtained for 16 skin conditions and both sexes in Iran and 15 surrounding countries. The sociodemographic index (SDI) for each country was also correlated with skin disease DALY rate using the Pearson coefficient (r) with two-tailed P-value.

RESULTS: There was no significant correlation between individual skin diseases and SDI. Acne and dermatitis caused the greatest burden and BCC the lowest burden of skin diseases in Iran and the other 15 countries. SCC and BCC were responsible for the largest discrepancy by sex, with higher burden in males compared to females.

CONCLUSION: Skin diseases, particularly dermatitis and acne, cause considerable burden in Iran and surrounding regions. Objective and transparent epidemiologic data such as GBD has the potential to inform and impact many facets of healthcare, research prioritization, public policy, and international partnerships.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Journal Article
in
Archives of Iranian Medicine
volume
20
issue
7
pages
12 pages
publisher
Academy of Medical Sciences of I.R. Iran
external identifiers
  • pmid:28745904
  • scopus:85025808014
ISSN
1029-2977
language
English
LU publication?
yes
id
4953b3c6-9bf9-4904-ba53-4648296d1d4e
date added to LUP
2017-08-13 01:36:26
date last changed
2024-03-17 18:53:30
@article{4953b3c6-9bf9-4904-ba53-4648296d1d4e,
  abstract     = {{<p>BACKGROUND: Iran and its neighboring countries represent four world regions with unique cultures and geography. Skin diseases span a wide diversity of etiologies including infectious, inflammatory, autoimmune, vascular, neurogenic, and oncologic. The Global Burden of Disease Study (GBD) 2015 measures the burden from skin diseases in 195 countries.</p><p>METHODS: Epidemiologic data were collected from literature review, survey data, and hospital inpatient/outpatient claims data. These raw data entered modeling using a Bayesian meta-regression tool, DisMod MR-2.1, which yielded prevalence estimates by age/sex/location/year. Prevalence estimates were combined with disability weights to yield years lived with disability (YLDs). YLDs are combined with years of life lost (YLLs), from mortality estimates, to yield disability-adjusted life years (DALYs). DALYs were obtained for 16 skin conditions and both sexes in Iran and 15 surrounding countries. The sociodemographic index (SDI) for each country was also correlated with skin disease DALY rate using the Pearson coefficient (r) with two-tailed P-value.</p><p>RESULTS: There was no significant correlation between individual skin diseases and SDI. Acne and dermatitis caused the greatest burden and BCC the lowest burden of skin diseases in Iran and the other 15 countries. SCC and BCC were responsible for the largest discrepancy by sex, with higher burden in males compared to females.</p><p>CONCLUSION: Skin diseases, particularly dermatitis and acne, cause considerable burden in Iran and surrounding regions. Objective and transparent epidemiologic data such as GBD has the potential to inform and impact many facets of healthcare, research prioritization, public policy, and international partnerships.</p>}},
  author       = {{Karimkhani, Chante and Dellavalle, Robert P. and Karimi, Seyed M and Rahimi-Movaghar, Vafa and Pourmalek, Farshad and Ahmad Kiadaliri, Aliasghar and Sahraian, Mohammad Ali and Roshandel, Gholamreza and Fereshtehnejad, Seyed-Mohammad and Qorbani, Mostafa and Radfar, Amir and Farvid, Maryam S and Asayesh, Hamid and Sepanlou, Sadaf G. and Djalalinia, Shirin and Kasaeian, Amir and Khubchandani, Jagdish and Malekzadeh, Reza and Moradi-Lakeh, Maziar and Krohn, Kristopher J and Mokdad, Ali H. and Vos, Theo and Naghavi, Mohsen}},
  issn         = {{1029-2977}},
  keywords     = {{Journal Article}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{429--440}},
  publisher    = {{Academy of Medical Sciences of I.R. Iran}},
  series       = {{Archives of Iranian Medicine}},
  title        = {{Burden of Skin and Subcutaneous Diseases in Iran and Neighboring Countries : Results from the Global Burden of Disease Study 2015}},
  volume       = {{20}},
  year         = {{2017}},
}