Combined Semilunar Valve Stenoses in Neonates: Management Approaches and Literature Review
(2014) In Pediatric Cardiology 35(8). p.1469-1473- Abstract
- Combination of right and left ventricular outflow tracts obstruction is extremely rare. Neonates with combined aortic stenosis (AS) and pulmonary stenosis (PS) present in critical condition and required urgent treatment. The management approach is not well defined. We report five female neonates with combined AS and PS presented to our institute in the last 5 years, age (1-18 days), weight (2.2-3.4 kg). Two had associated muscular ventricular septal defects. The mean Doppler gradient across the aortic valve (AV) was 73 mmHg (53-105 mmHg) and across the pulmonary valve was 62 mmHg (44-76 mmHg). Three had balloon dilatation and one surgical repair. The fifth patient was managed conservatively, but had sudden cardiac death at age of 3 months.... (More)
- Combination of right and left ventricular outflow tracts obstruction is extremely rare. Neonates with combined aortic stenosis (AS) and pulmonary stenosis (PS) present in critical condition and required urgent treatment. The management approach is not well defined. We report five female neonates with combined AS and PS presented to our institute in the last 5 years, age (1-18 days), weight (2.2-3.4 kg). Two had associated muscular ventricular septal defects. The mean Doppler gradient across the aortic valve (AV) was 73 mmHg (53-105 mmHg) and across the pulmonary valve was 62 mmHg (44-76 mmHg). Three had balloon dilatation and one surgical repair. The fifth patient was managed conservatively, but had sudden cardiac death at age of 3 months. One patient arrived in shock and sepsis, underwent emergency balloon dilation of the AV in the ICU. Despite decreasing the gradient, she died next day after the procedure. The surviving children were well at median follow-up age of 3.4 years. This is an extremely rare combination which needs early intervention. The management approach is not well defined. Interventional catheterization is possibly the better option. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4982951
- author
- Elhoury, Motea E. ; El-Segaier, Milad LU ; Momenah, Tarek and Galal, Mohammed Omar
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Pulmonary valve stenosis, Aortic valve stenosis, Balloon valvuloplasty
- in
- Pediatric Cardiology
- volume
- 35
- issue
- 8
- pages
- 1469 - 1473
- publisher
- Springer
- external identifiers
-
- wos:000345333100023
- scopus:84939894533
- pmid:25124720
- ISSN
- 0172-0643
- DOI
- 10.1007/s00246-014-1000-9
- language
- English
- LU publication?
- yes
- id
- c3ad25d2-4d9c-47af-a0c5-eb1ac4bfb416 (old id 4982951)
- date added to LUP
- 2016-04-01 09:53:26
- date last changed
- 2022-01-25 17:41:35
@article{c3ad25d2-4d9c-47af-a0c5-eb1ac4bfb416, abstract = {{Combination of right and left ventricular outflow tracts obstruction is extremely rare. Neonates with combined aortic stenosis (AS) and pulmonary stenosis (PS) present in critical condition and required urgent treatment. The management approach is not well defined. We report five female neonates with combined AS and PS presented to our institute in the last 5 years, age (1-18 days), weight (2.2-3.4 kg). Two had associated muscular ventricular septal defects. The mean Doppler gradient across the aortic valve (AV) was 73 mmHg (53-105 mmHg) and across the pulmonary valve was 62 mmHg (44-76 mmHg). Three had balloon dilatation and one surgical repair. The fifth patient was managed conservatively, but had sudden cardiac death at age of 3 months. One patient arrived in shock and sepsis, underwent emergency balloon dilation of the AV in the ICU. Despite decreasing the gradient, she died next day after the procedure. The surviving children were well at median follow-up age of 3.4 years. This is an extremely rare combination which needs early intervention. The management approach is not well defined. Interventional catheterization is possibly the better option.}}, author = {{Elhoury, Motea E. and El-Segaier, Milad and Momenah, Tarek and Galal, Mohammed Omar}}, issn = {{0172-0643}}, keywords = {{Pulmonary valve stenosis; Aortic valve stenosis; Balloon valvuloplasty}}, language = {{eng}}, number = {{8}}, pages = {{1469--1473}}, publisher = {{Springer}}, series = {{Pediatric Cardiology}}, title = {{Combined Semilunar Valve Stenoses in Neonates: Management Approaches and Literature Review}}, url = {{http://dx.doi.org/10.1007/s00246-014-1000-9}}, doi = {{10.1007/s00246-014-1000-9}}, volume = {{35}}, year = {{2014}}, }