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Physiology of chemoheterotrophic thermoanaerobes

van Niel, Ed LU ; Scully, Sean M and Örlygsson, Johann (2023) In Grand challenges in biology and biotechnology p.133-151
Abstract
The industry is increasingly discovering the potential of strict anaerobic thermophilic bacteria, as there are many applications to consider, including the production of stable thermozymes and degradation of lignocellulosic materials, proteins, and alkanes. However, the metabolism of these thermoanaerobes is still poorly understood and so far, there is comprehensive knowledge of only a few model species. Of the studies published to date, the vast majority have focused almost exclusively on the anaerobic catabolism of carbohydrates, including polysaccharides, hexoses, pentoses, and disaccharides. While research on the fermentation of proteins and amino acids has enjoyed some recent developments, the exploration of the degradation of lipids... (More)
The industry is increasingly discovering the potential of strict anaerobic thermophilic bacteria, as there are many applications to consider, including the production of stable thermozymes and degradation of lignocellulosic materials, proteins, and alkanes. However, the metabolism of these thermoanaerobes is still poorly understood and so far, there is comprehensive knowledge of only a few model species. Of the studies published to date, the vast majority have focused almost exclusively on the anaerobic catabolism of carbohydrates, including polysaccharides, hexoses, pentoses, and disaccharides. While research on the fermentation of proteins and amino acids has enjoyed some recent developments, the exploration of the degradation of lipids and alkanes under these conditions has only just begun. In this chapter, the different central carbon pathways are discussed along with the utilization of alternative intracellular energy carriers other than ATP, namely GTP and pyrophosphate. Subsequent steps and approaches in deeper understanding of the physiology are concisely discussed. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
amino acid fermentation, central carbon pathways, energy carriers, genetic engineering, proteolytic thermophiles, lignocellulose degradation
host publication
Thermophilic Anaerobes : Phylogeny, Physiology and Biotechnological Applications - Phylogeny, Physiology and Biotechnological Applications
series title
Grand challenges in biology and biotechnology
editor
Scully, Sean M and Örlygsson, Johann
pages
19 pages
publisher
Springer
ISBN
978-3-031-41719-1
978-3-031-41720-7
DOI
10.1007/978-3-031-41720-7_5
language
English
LU publication?
yes
id
4b227e38-a29f-4b0c-b0d2-611cd11dcbea
date added to LUP
2023-11-15 10:35:19
date last changed
2023-11-17 11:22:11
@inbook{4b227e38-a29f-4b0c-b0d2-611cd11dcbea,
  abstract     = {{The industry is increasingly discovering the potential of strict anaerobic thermophilic bacteria, as there are many applications to consider, including the production of stable thermozymes and degradation of lignocellulosic materials, proteins, and alkanes. However, the metabolism of these thermoanaerobes is still poorly understood and so far, there is comprehensive knowledge of only a few model species. Of the studies published to date, the vast majority have focused almost exclusively on the anaerobic catabolism of carbohydrates, including polysaccharides, hexoses, pentoses, and disaccharides. While research on the fermentation of proteins and amino acids has enjoyed some recent developments, the exploration of the degradation of lipids and alkanes under these conditions has only just begun. In this chapter, the different central carbon pathways are discussed along with the utilization of alternative intracellular energy carriers other than ATP, namely GTP and pyrophosphate. Subsequent steps and approaches in deeper understanding of the physiology are concisely discussed.}},
  author       = {{van Niel, Ed and Scully, Sean M and Örlygsson, Johann}},
  booktitle    = {{Thermophilic Anaerobes : Phylogeny, Physiology and Biotechnological Applications}},
  editor       = {{Scully, Sean M and Örlygsson, Johann}},
  isbn         = {{978-3-031-41719-1}},
  keywords     = {{amino acid fermentation; central carbon pathways; energy carriers; genetic engineering; proteolytic thermophiles; lignocellulose degradation}},
  language     = {{eng}},
  pages        = {{133--151}},
  publisher    = {{Springer}},
  series       = {{Grand challenges in biology and biotechnology}},
  title        = {{Physiology of chemoheterotrophic thermoanaerobes}},
  url          = {{http://dx.doi.org/10.1007/978-3-031-41720-7_5}},
  doi          = {{10.1007/978-3-031-41720-7_5}},
  year         = {{2023}},
}