Biopsy sampling requirements for the estimation of muscle capillarization
(2002) In Muscle and Nerve 26(4). p.546-548- Abstract
- The aim of this study was to determine the number of tibialis anterior biopsy samples and muscle fibers required to estimate the capillary supply of individual muscle fibers (C:F-i). C:F-i was calculated for 25 type 1 fibers in each of 8 images from 3 biopsies of 5 young healthy individuals. Sequential estimation analysis indicated that 50 fibers from one biopsy are sufficient to characterize the C:F-i of the tibialis anterior for a group of subjects. Thus, when analyzing the capillarization of the tibialis anterior, the requirements of only one biopsy sample and 50 fibers means a great reduction in time for analysis and in the invasiveness of the procedure. (C) 2002 Wiley Periodicals, Inc.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/325976
- author
- Porter, MM ; Koolage, CW and Lexell, Jan LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- biopsy methods, capillaries, skeletal, muscle
- in
- Muscle and Nerve
- volume
- 26
- issue
- 4
- pages
- 546 - 548
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:12362422
- wos:000178385500015
- scopus:0036788647
- ISSN
- 0148-639X
- DOI
- 10.1002/mus.10221
- language
- English
- LU publication?
- yes
- id
- 4c152628-7215-43fb-b3ee-3ac9bd21ad55 (old id 325976)
- date added to LUP
- 2016-04-01 11:50:20
- date last changed
- 2022-01-26 18:58:02
@article{4c152628-7215-43fb-b3ee-3ac9bd21ad55, abstract = {{The aim of this study was to determine the number of tibialis anterior biopsy samples and muscle fibers required to estimate the capillary supply of individual muscle fibers (C:F-i). C:F-i was calculated for 25 type 1 fibers in each of 8 images from 3 biopsies of 5 young healthy individuals. Sequential estimation analysis indicated that 50 fibers from one biopsy are sufficient to characterize the C:F-i of the tibialis anterior for a group of subjects. Thus, when analyzing the capillarization of the tibialis anterior, the requirements of only one biopsy sample and 50 fibers means a great reduction in time for analysis and in the invasiveness of the procedure. (C) 2002 Wiley Periodicals, Inc.}}, author = {{Porter, MM and Koolage, CW and Lexell, Jan}}, issn = {{0148-639X}}, keywords = {{biopsy methods; capillaries; skeletal; muscle}}, language = {{eng}}, number = {{4}}, pages = {{546--548}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Muscle and Nerve}}, title = {{Biopsy sampling requirements for the estimation of muscle capillarization}}, url = {{http://dx.doi.org/10.1002/mus.10221}}, doi = {{10.1002/mus.10221}}, volume = {{26}}, year = {{2002}}, }