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Comparison of photon-counting CT with energy-integrating CT in temporal bone imaging : an anthropomorphic phantom study

Pellby, David LU ; Vestin-Fredriksson, Malin ; Rönnblom, Anton ; Nilsson, Margareta LU ; Siemund, Roger LU ; Kull, Love and Aurumskjöld, Marie Louise LU (2026) In Acta Radiologica
Abstract

Background: Photon-counting computed tomography (PCCT) is an emerging technique under evaluation for temporal bone imaging. Its capacity for radiation dose reduction while maintaining diagnostic image quality (IQ) requires further study. Purpose: To evaluate how PCCT compares to energy-integrating CT (EICT) in temporal bone imaging in terms of IQ and visualization of anatomical landmarks, at a clinically relevant, reduced radiation dose. Material and Methods: An anthropomorphic phantom with exchangeable fresh frozen human temporal bone specimens was scanned. Nine specimens were scanned on a PCCT system with clinical protocol settings, followed by stepwise dose reductions for one specimen. Ten specimens were scanned on a EICT system with... (More)

Background: Photon-counting computed tomography (PCCT) is an emerging technique under evaluation for temporal bone imaging. Its capacity for radiation dose reduction while maintaining diagnostic image quality (IQ) requires further study. Purpose: To evaluate how PCCT compares to energy-integrating CT (EICT) in temporal bone imaging in terms of IQ and visualization of anatomical landmarks, at a clinically relevant, reduced radiation dose. Material and Methods: An anthropomorphic phantom with exchangeable fresh frozen human temporal bone specimens was scanned. Nine specimens were scanned on a PCCT system with clinical protocol settings, followed by stepwise dose reductions for one specimen. Ten specimens were scanned on a EICT system with clinical protocol settings. Three readers assessed overall IQ and visualization of 10 important anatomical landmarks on a 4-point scale. Results: PCCT was preferred by readers for most landmarks and ranked higher in overall IQ compared with EICT. At clinical protocol, PCCT provided statistically significant better results for all landmarks and overall IQ compared to EICT with dose reduction of almost 70%. With stepwise dose reduction PCCT maintained good to excellent IQ for most landmarks, suboptimal for the ossicular chain landmarks at lower doses, and overall poor image quality at the lowest dose level. PCCT at clinical and several reduced dose levels demonstrated statistically significant difference in overall image quality and visualization of landmarks, compared to EICT (P <0.05). Conclusion: PCCT provides improved diagnostic image quality compared to EICT at clinical protocols, with lowered radiation dose, indicating its suitability for temporal bone imaging.

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organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
anatomy, computed tomography, Ear, phantoms (imaging), radiation dosage
in
Acta Radiologica
publisher
SAGE Publications
external identifiers
  • pmid:41995623
  • scopus:105036245537
ISSN
0284-1851
DOI
10.1177/02841851261431600
language
English
LU publication?
yes
id
4c26073c-d3dc-43cf-86d5-ff3088b14e1e
date added to LUP
2026-05-25 10:44:53
date last changed
2026-05-26 03:00:07
@article{4c26073c-d3dc-43cf-86d5-ff3088b14e1e,
  abstract     = {{<p>Background: Photon-counting computed tomography (PCCT) is an emerging technique under evaluation for temporal bone imaging. Its capacity for radiation dose reduction while maintaining diagnostic image quality (IQ) requires further study. Purpose: To evaluate how PCCT compares to energy-integrating CT (EICT) in temporal bone imaging in terms of IQ and visualization of anatomical landmarks, at a clinically relevant, reduced radiation dose. Material and Methods: An anthropomorphic phantom with exchangeable fresh frozen human temporal bone specimens was scanned. Nine specimens were scanned on a PCCT system with clinical protocol settings, followed by stepwise dose reductions for one specimen. Ten specimens were scanned on a EICT system with clinical protocol settings. Three readers assessed overall IQ and visualization of 10 important anatomical landmarks on a 4-point scale. Results: PCCT was preferred by readers for most landmarks and ranked higher in overall IQ compared with EICT. At clinical protocol, PCCT provided statistically significant better results for all landmarks and overall IQ compared to EICT with dose reduction of almost 70%. With stepwise dose reduction PCCT maintained good to excellent IQ for most landmarks, suboptimal for the ossicular chain landmarks at lower doses, and overall poor image quality at the lowest dose level. PCCT at clinical and several reduced dose levels demonstrated statistically significant difference in overall image quality and visualization of landmarks, compared to EICT (P &lt;0.05). Conclusion: PCCT provides improved diagnostic image quality compared to EICT at clinical protocols, with lowered radiation dose, indicating its suitability for temporal bone imaging.</p>}},
  author       = {{Pellby, David and Vestin-Fredriksson, Malin and Rönnblom, Anton and Nilsson, Margareta and Siemund, Roger and Kull, Love and Aurumskjöld, Marie Louise}},
  issn         = {{0284-1851}},
  keywords     = {{anatomy; computed tomography; Ear; phantoms (imaging); radiation dosage}},
  language     = {{eng}},
  publisher    = {{SAGE Publications}},
  series       = {{Acta Radiologica}},
  title        = {{Comparison of photon-counting CT with energy-integrating CT in temporal bone imaging : an anthropomorphic phantom study}},
  url          = {{http://dx.doi.org/10.1177/02841851261431600}},
  doi          = {{10.1177/02841851261431600}},
  year         = {{2026}},
}