Fatigue During Cancer-Related Radiotherapy and Associations with Activities, Work Ability and Quality of Life : Paying Attention to Subgroups more Likely to Experience Fatigue
Tödt, Kristina LU ; Engström, Maria ; Ekström, Magnus LU
and Efverman, Anna
(2022)
In Integrative Cancer Therapies
21.
- Abstract
Background: Having knowledge of which patients are more likely to experience fatigue during radiotherapy and the relationship between fatigue and health-related quality of life (HRQL) is important to improve identification and care of patients experiencing burdensome fatigue. Objective: To identify subgroups of patients, varying in situational, physiological, and psychological factors, who are more likely to experience fatigue an ordinary week of radiotherapy, and to compare patients experiencing and not experiencing fatigue regarding perceived HRQL and functional performance, that is, daily and physical activity and work ability. Methods: Cross-sectional study of 457 patients (52% women) undergoing radiotherapy (38% breast, 32%... (More)
Background: Having knowledge of which patients are more likely to experience fatigue during radiotherapy and the relationship between fatigue and health-related quality of life (HRQL) is important to improve identification and care of patients experiencing burdensome fatigue. Objective: To identify subgroups of patients, varying in situational, physiological, and psychological factors, who are more likely to experience fatigue an ordinary week of radiotherapy, and to compare patients experiencing and not experiencing fatigue regarding perceived HRQL and functional performance, that is, daily and physical activity and work ability. Methods: Cross-sectional study of 457 patients (52% women) undergoing radiotherapy (38% breast, 32% prostate cancer), using self-reported questionnaire data on fatigue, HRQL and functional performance analyzed using multivariable regression models. Results: Of the 448 patients who answered the fatigue question, 321 (72%) experienced fatigue. Patients reporting any comorbidity or depressed mood were more likely to experience fatigue, relative risk (RR) 1.56 ([95% confidence interval (CI)] 1.13-2.16) and RR 2.57 (CI 1.73-3.83), respectively. Patients with fatigue reported worse HRQL and performed less physical activity, including daily (P =.003), vigorous (P =.003) and moderate (P =.002) activity. Patients with and without fatigue reported 60% versus 40% sickness absence. Conclusion: Patients with depressed mood or comorbidity were more likely to experience fatigue an ordinary week of radiotherapy than other patients were. Patients experiencing fatigue perceived worse HRQL and performed less daily and physical activity compared to patients not experiencing fatigue. Cancer care practitioners may consider paying extra attention to these subgroups of patients.
(Less)
- author
- Tödt, Kristina
LU
; Engström, Maria
; Ekström, Magnus
LU
and Efverman, Anna
- organization
- publishing date
- 2022-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- activities of daily living, cancer survivors, fatigue, oncology nursing, physical activity, quality of life, radiotherapy, work ability
- in
- Integrative Cancer Therapies
- volume
- 21
- publisher
- SAGE Publications
- external identifiers
-
- pmid:36444775
- scopus:85142872542
- ISSN
- 1534-7354
- DOI
- 10.1177/15347354221138576
- language
- English
- LU publication?
- yes
- id
- 4cc6a1b5-a129-4441-84dc-7ae938727dfd
- date added to LUP
- 2022-12-27 11:00:25
- date last changed
- 2024-04-04 14:43:20
@article{4cc6a1b5-a129-4441-84dc-7ae938727dfd,
abstract = {{<p>Background: Having knowledge of which patients are more likely to experience fatigue during radiotherapy and the relationship between fatigue and health-related quality of life (HRQL) is important to improve identification and care of patients experiencing burdensome fatigue. Objective: To identify subgroups of patients, varying in situational, physiological, and psychological factors, who are more likely to experience fatigue an ordinary week of radiotherapy, and to compare patients experiencing and not experiencing fatigue regarding perceived HRQL and functional performance, that is, daily and physical activity and work ability. Methods: Cross-sectional study of 457 patients (52% women) undergoing radiotherapy (38% breast, 32% prostate cancer), using self-reported questionnaire data on fatigue, HRQL and functional performance analyzed using multivariable regression models. Results: Of the 448 patients who answered the fatigue question, 321 (72%) experienced fatigue. Patients reporting any comorbidity or depressed mood were more likely to experience fatigue, relative risk (RR) 1.56 ([95% confidence interval (CI)] 1.13-2.16) and RR 2.57 (CI 1.73-3.83), respectively. Patients with fatigue reported worse HRQL and performed less physical activity, including daily (P =.003), vigorous (P =.003) and moderate (P =.002) activity. Patients with and without fatigue reported 60% versus 40% sickness absence. Conclusion: Patients with depressed mood or comorbidity were more likely to experience fatigue an ordinary week of radiotherapy than other patients were. Patients experiencing fatigue perceived worse HRQL and performed less daily and physical activity compared to patients not experiencing fatigue. Cancer care practitioners may consider paying extra attention to these subgroups of patients.</p>}},
author = {{Tödt, Kristina and Engström, Maria and Ekström, Magnus and Efverman, Anna}},
issn = {{1534-7354}},
keywords = {{activities of daily living; cancer survivors; fatigue; oncology nursing; physical activity; quality of life; radiotherapy; work ability}},
language = {{eng}},
publisher = {{SAGE Publications}},
series = {{Integrative Cancer Therapies}},
title = {{Fatigue During Cancer-Related Radiotherapy and Associations with Activities, Work Ability and Quality of Life : Paying Attention to Subgroups more Likely to Experience Fatigue}},
url = {{http://dx.doi.org/10.1177/15347354221138576}},
doi = {{10.1177/15347354221138576}},
volume = {{21}},
year = {{2022}},
}