Unraveling the brain's response to COVID-19 : How SARS-CoV-2 afflicts dopaminergic neurons
(2024) In Cell Stem Cell 31(2). p.152-154- Abstract
COVID-19 patients often display dysfunctions of the nervous system, indicating an effect of SARS-CoV-2 on neural cells. Yang et al. now show that human stem-cell-derived dopaminergic neurons are susceptible to SARS-CoV-2, triggering inflammation and senescence. The study further identifies three FDA-approved drugs capable of reversing these cellular phenotypes.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4cdf59d9-bdd6-4891-9461-98dcf304184f
- author
- Eidhof, Ilse ; Twohig, Daniel LU and Falk, Anna LU
- organization
- publishing date
- 2024-02-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cell Stem Cell
- volume
- 31
- issue
- 2
- pages
- 3 pages
- publisher
- Cell Press
- external identifiers
-
- pmid:38306990
- scopus:85183508324
- ISSN
- 1934-5909
- DOI
- 10.1016/j.stem.2024.01.002
- language
- English
- LU publication?
- yes
- id
- 4cdf59d9-bdd6-4891-9461-98dcf304184f
- date added to LUP
- 2024-02-19 15:03:02
- date last changed
- 2024-04-19 17:06:23
@misc{4cdf59d9-bdd6-4891-9461-98dcf304184f, abstract = {{<p>COVID-19 patients often display dysfunctions of the nervous system, indicating an effect of SARS-CoV-2 on neural cells. Yang et al. now show that human stem-cell-derived dopaminergic neurons are susceptible to SARS-CoV-2, triggering inflammation and senescence. The study further identifies three FDA-approved drugs capable of reversing these cellular phenotypes.</p>}}, author = {{Eidhof, Ilse and Twohig, Daniel and Falk, Anna}}, issn = {{1934-5909}}, language = {{eng}}, month = {{02}}, number = {{2}}, pages = {{152--154}}, publisher = {{Cell Press}}, series = {{Cell Stem Cell}}, title = {{Unraveling the brain's response to COVID-19 : How SARS-CoV-2 afflicts dopaminergic neurons}}, url = {{http://dx.doi.org/10.1016/j.stem.2024.01.002}}, doi = {{10.1016/j.stem.2024.01.002}}, volume = {{31}}, year = {{2024}}, }