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Thoughts on the interpretation of positive photopatch test reactions

Bruze, Magnus LU (2020) In European journal of dermatology : EJD 30(5). p.541-544
Abstract

BACKGROUND: Positive photopatch test reactions are classified according to the International Contact Dermatitis Group. The various reaction patterns are interpreted to represent patterns such as contact allergy, photocontact allergy, photoaugmentation, and photoinhibition. OBJECTIVE: To investigate whether there are any weaknesses in the interpretation of reaction patterns. MATERIALS & METHODS: A dermatitis patient with photoallergic contact dermatitis due to ketoprofen was photopatch tested with serial dilutions of ketoprofen in ethanol. The reaction patterns for the various concentrations were used as a basis for discussion on weaknesses regarding the present interpretations of positive photopatch test reactions. RESULTS: The... (More)

BACKGROUND: Positive photopatch test reactions are classified according to the International Contact Dermatitis Group. The various reaction patterns are interpreted to represent patterns such as contact allergy, photocontact allergy, photoaugmentation, and photoinhibition. OBJECTIVE: To investigate whether there are any weaknesses in the interpretation of reaction patterns. MATERIALS & METHODS: A dermatitis patient with photoallergic contact dermatitis due to ketoprofen was photopatch tested with serial dilutions of ketoprofen in ethanol. The reaction patterns for the various concentrations were used as a basis for discussion on weaknesses regarding the present interpretations of positive photopatch test reactions. RESULTS: The reaction patterns to the ketoprofen photopatch at various concentrations were interpreted as (i) contact allergy, (ii) contact allergy with photoaugmentation, (iii) contact allergy and photocontact allergy, and (iv) photocontact allergy. CONCLUSION: The present interpretation of positive photopatch test reactions is unreliable and therefore insufficient regarding appropriate advice for patients.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
interpretation, ketoprofen, photoallergic contact dermatitis, photopatch testing
in
European journal of dermatology : EJD
volume
30
issue
5
pages
4 pages
publisher
John Libbey Eurotext
external identifiers
  • scopus:85096202859
  • pmid:33021476
ISSN
1167-1122
DOI
10.1684/ejd.2020.3877
language
English
LU publication?
yes
id
4d5e0f6c-031a-460b-a8b2-6f61ffd20c11
date added to LUP
2021-01-14 16:40:40
date last changed
2024-10-03 17:15:27
@article{4d5e0f6c-031a-460b-a8b2-6f61ffd20c11,
  abstract     = {{<p>BACKGROUND: Positive photopatch test reactions are classified according to the International Contact Dermatitis Group. The various reaction patterns are interpreted to represent patterns such as contact allergy, photocontact allergy, photoaugmentation, and photoinhibition. OBJECTIVE: To investigate whether there are any weaknesses in the interpretation of reaction patterns. MATERIALS &amp; METHODS: A dermatitis patient with photoallergic contact dermatitis due to ketoprofen was photopatch tested with serial dilutions of ketoprofen in ethanol. The reaction patterns for the various concentrations were used as a basis for discussion on weaknesses regarding the present interpretations of positive photopatch test reactions. RESULTS: The reaction patterns to the ketoprofen photopatch at various concentrations were interpreted as (i) contact allergy, (ii) contact allergy with photoaugmentation, (iii) contact allergy and photocontact allergy, and (iv) photocontact allergy. CONCLUSION: The present interpretation of positive photopatch test reactions is unreliable and therefore insufficient regarding appropriate advice for patients.</p>}},
  author       = {{Bruze, Magnus}},
  issn         = {{1167-1122}},
  keywords     = {{interpretation; ketoprofen; photoallergic contact dermatitis; photopatch testing}},
  language     = {{eng}},
  month        = {{10}},
  number       = {{5}},
  pages        = {{541--544}},
  publisher    = {{John Libbey Eurotext}},
  series       = {{European journal of dermatology : EJD}},
  title        = {{Thoughts on the interpretation of positive photopatch test reactions}},
  url          = {{http://dx.doi.org/10.1684/ejd.2020.3877}},
  doi          = {{10.1684/ejd.2020.3877}},
  volume       = {{30}},
  year         = {{2020}},
}