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Effect of BCG and allogeneic tumour cells on adenovirus type 12 tumorigenesis in mice

Sjögren, Hans O. LU and Ankerst, Jaro LU orcid (1969) In Nature 221(5183). p.863-864
Abstract

HAMSTERS and mice inoculated at birth with tumour viruses have been used in studies of the prophylactic effects of various treatments during the latent period. The incidence of primary tumours in hamsters infected at birth with SV40 is reduced if the virus is inoculated during the latent period1-3. Similar administration of adenovirus type 12 also inhibited the induction of tumours by SV404; this was taken as an indication of a cross-reaction between the tumour-specific transplantation antigens (TSTA) of SV40 and adeno 12 virus tumours. X-irradiated SV40 tumour cells which did not contain infectious virus were also effective in reducing the frequency of primary SV40 tumours when given at various times before tumour... (More)

HAMSTERS and mice inoculated at birth with tumour viruses have been used in studies of the prophylactic effects of various treatments during the latent period. The incidence of primary tumours in hamsters infected at birth with SV40 is reduced if the virus is inoculated during the latent period1-3. Similar administration of adenovirus type 12 also inhibited the induction of tumours by SV404; this was taken as an indication of a cross-reaction between the tumour-specific transplantation antigens (TSTA) of SV40 and adeno 12 virus tumours. X-irradiated SV40 tumour cells which did not contain infectious virus were also effective in reducing the frequency of primary SV40 tumours when given at various times before tumour development2,5.

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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nature
volume
221
issue
5183
pages
863 - 864
publisher
Nature Publishing Group
external identifiers
  • pmid:4303807
  • scopus:0014478720
ISSN
0028-0836
DOI
10.1038/221863a0
language
English
LU publication?
yes
id
4db06464-d1db-4f84-b02f-aa6005988d52
date added to LUP
2021-02-01 11:44:50
date last changed
2024-01-03 06:01:16
@article{4db06464-d1db-4f84-b02f-aa6005988d52,
  abstract     = {{<p>HAMSTERS and mice inoculated at birth with tumour viruses have been used in studies of the prophylactic effects of various treatments during the latent period. The incidence of primary tumours in hamsters infected at birth with SV40 is reduced if the virus is inoculated during the latent period<sup>1-3</sup>. Similar administration of adenovirus type 12 also inhibited the induction of tumours by SV40<sup>4</sup>; this was taken as an indication of a cross-reaction between the tumour-specific transplantation antigens (TSTA) of SV40 and adeno 12 virus tumours. X-irradiated SV40 tumour cells which did not contain infectious virus were also effective in reducing the frequency of primary SV40 tumours when given at various times before tumour development<sup>2,5</sup>.</p>}},
  author       = {{Sjögren, Hans O. and Ankerst, Jaro}},
  issn         = {{0028-0836}},
  language     = {{eng}},
  number       = {{5183}},
  pages        = {{863--864}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Nature}},
  title        = {{Effect of BCG and allogeneic tumour cells on adenovirus type 12 tumorigenesis in mice}},
  url          = {{http://dx.doi.org/10.1038/221863a0}},
  doi          = {{10.1038/221863a0}},
  volume       = {{221}},
  year         = {{1969}},
}