Quantification of myocardial hypoperfusion with 99m Tc-sestamibi in patients undergoing prolonged coronary artery balloon occlusion.
(2002) In Nuclear Medicine Communications 23(3). p.219-228- Abstract
- SUMMARY: Percutaneous transluminal coronary angioplasty provides an excellent opportunity to investigate the location and quantity of hypoperfusion during sudden complete occlusion of one of the major coronary arteries. Thirty-five patients referred for elective percutaneous transluminal coronary angioplasty were injected intravenously with 99mTc-sestamibi during balloon inflation. To visualize and quantify the hypoperfused region, a map of perfusion was constructed from that occlusion study and from the control study performed on the following day. Patients were divided into groups according to proximal or distal occlusion within each of the three coronary arteries. The region of myocardium supplied by each coronary artery varied in... (More)
- SUMMARY: Percutaneous transluminal coronary angioplasty provides an excellent opportunity to investigate the location and quantity of hypoperfusion during sudden complete occlusion of one of the major coronary arteries. Thirty-five patients referred for elective percutaneous transluminal coronary angioplasty were injected intravenously with 99mTc-sestamibi during balloon inflation. To visualize and quantify the hypoperfused region, a map of perfusion was constructed from that occlusion study and from the control study performed on the following day. Patients were divided into groups according to proximal or distal occlusion within each of the three coronary arteries. The region of myocardium supplied by each coronary artery varied in location and extended outside the typical borders for all arteries, but most prominently for the left circumflex coronary artery. The quantities of hypoperfusion varied within each artery group, but the average hypoperfusion was greater for the left anterior descending coronary artery than for either the right coronary artery or the left circumflex coronary artery. It is concluded that the quantities of hypoperfusion were highly variable within each artery group. Occlusion of the left anterior descending coronary artery was associated with the largest ischaemic region. The area of hypoperfusion extended outside the typical borders, most prominently for the left circumflex coronary artery. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/106042
- author
- Persson, Eva LU ; Palmer, John LU ; Pettersson, J. ; Warren, S. ; Borges-Neto, S. ; Wagner, G. and Pahlm, O.
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nuclear Medicine Communications
- volume
- 23
- issue
- 3
- pages
- 219 - 228
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:11891479
- wos:000174534300004
- scopus:0036100445
- ISSN
- 1473-5628
- language
- English
- LU publication?
- yes
- id
- 4e254bca-3cd7-41be-8c40-4e7413c2f6a9 (old id 106042)
- alternative location
- http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11891479&dopt=Abstract
- date added to LUP
- 2016-04-01 12:34:32
- date last changed
- 2022-01-27 07:00:39
@article{4e254bca-3cd7-41be-8c40-4e7413c2f6a9,
abstract = {{SUMMARY: Percutaneous transluminal coronary angioplasty provides an excellent opportunity to investigate the location and quantity of hypoperfusion during sudden complete occlusion of one of the major coronary arteries. Thirty-five patients referred for elective percutaneous transluminal coronary angioplasty were injected intravenously with 99mTc-sestamibi during balloon inflation. To visualize and quantify the hypoperfused region, a map of perfusion was constructed from that occlusion study and from the control study performed on the following day. Patients were divided into groups according to proximal or distal occlusion within each of the three coronary arteries. The region of myocardium supplied by each coronary artery varied in location and extended outside the typical borders for all arteries, but most prominently for the left circumflex coronary artery. The quantities of hypoperfusion varied within each artery group, but the average hypoperfusion was greater for the left anterior descending coronary artery than for either the right coronary artery or the left circumflex coronary artery. It is concluded that the quantities of hypoperfusion were highly variable within each artery group. Occlusion of the left anterior descending coronary artery was associated with the largest ischaemic region. The area of hypoperfusion extended outside the typical borders, most prominently for the left circumflex coronary artery.}},
author = {{Persson, Eva and Palmer, John and Pettersson, J. and Warren, S. and Borges-Neto, S. and Wagner, G. and Pahlm, O.}},
issn = {{1473-5628}},
language = {{eng}},
number = {{3}},
pages = {{219--228}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Nuclear Medicine Communications}},
title = {{Quantification of myocardial hypoperfusion with 99m Tc-sestamibi in patients undergoing prolonged coronary artery balloon occlusion.}},
url = {{http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11891479&dopt=Abstract}},
volume = {{23}},
year = {{2002}},
}