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Synthesis of mannose oligosaccharides via reversal of the α-mannosidase reaction

Johansson, Elisabet ; Hedbys, Lars ; Larsson, Per-Olof LU ; Mosbach, Klaus LU ; Gunnarsson, Alf and Svensson, Sigfrid (1986) In Biotechnology Letters 8. p.421-424
Abstract
Three naturally occurring isomers of the disaccharideO-α-D-mannosyl-D-mannoside were synthesized by reversing the hydrolytic activity of jack bean α-mannosidase at 75°C in a very high concentration of mannose. Higher oligosaccharides were also obtained at the later stages of the reaction. The maximum total yield of disaccharides was 37% (w/w) based on the total amount of saccharides.
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
reversed mannosidase reaction, disaccharide synthesis, jack bean mannosidase
in
Biotechnology Letters
volume
8
pages
4 pages
publisher
Springer
external identifiers
  • scopus:0022588639
ISSN
0951-208X
DOI
10.1007/BF01026746
language
English
LU publication?
yes
id
4e598c81-b7aa-479f-aa4c-bddb2d5f643b
date added to LUP
2024-06-18 15:01:43
date last changed
2024-09-06 13:07:56
@article{4e598c81-b7aa-479f-aa4c-bddb2d5f643b,
  abstract     = {{Three naturally occurring isomers of the disaccharideO-α-D-mannosyl-D-mannoside were synthesized by reversing the hydrolytic activity of jack bean α-mannosidase at 75°C in a very high concentration of mannose. Higher oligosaccharides were also obtained at the later stages of the reaction. The maximum total yield of disaccharides was 37% (w/w) based on the total amount of saccharides.}},
  author       = {{Johansson, Elisabet and Hedbys, Lars and Larsson, Per-Olof and Mosbach, Klaus and Gunnarsson, Alf and Svensson, Sigfrid}},
  issn         = {{0951-208X}},
  keywords     = {{reversed mannosidase reaction; disaccharide synthesis; jack bean mannosidase}},
  language     = {{eng}},
  pages        = {{421--424}},
  publisher    = {{Springer}},
  series       = {{Biotechnology Letters}},
  title        = {{Synthesis of mannose oligosaccharides via reversal of the α-mannosidase reaction}},
  url          = {{http://dx.doi.org/10.1007/BF01026746}},
  doi          = {{10.1007/BF01026746}},
  volume       = {{8}},
  year         = {{1986}},
}