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Gender and age differences in symptoms and health-related quality of life in patients with atrial fibrillation referred for catheter ablation

Walfridsson, Ulla ; Steen Hansen, Peter ; Charitakis, Emmanouil ; Almroth, Henrik ; Jönsson, Anders ; Karlsson, Lars O. ; Liuba, Ioan ; Samo Ayou, Romeo ; Poci, Dritan and Holmqvist, Fredrik LU , et al. (2019) In PACE - Pacing and Clinical Electrophysiology 42(11). p.1431-1439
Abstract

Background: Primary indication for catheter ablation of atrial fibrillation (AF) is to reduce symptoms and improve health-related quality of life (HRQoL). There are data showing differences between the genders and between younger and older patients. To evaluate this, we studied a large Scandinavian cohort of patients referred for catheter ablation of AF. Methods: Consecutive patients filled out the ASTA questionnaire, assessing symptoms, HRQoL, and perception of arrhythmia, prior to ablation. Patients were recruited from four Swedish and one Danish tertiary center. Results: A total of 2493 patients (72% men) filled out the ASTA questionnaire. Women experienced eight of the nine ASTA scale symptoms more often than men. Patients <65... (More)

Background: Primary indication for catheter ablation of atrial fibrillation (AF) is to reduce symptoms and improve health-related quality of life (HRQoL). There are data showing differences between the genders and between younger and older patients. To evaluate this, we studied a large Scandinavian cohort of patients referred for catheter ablation of AF. Methods: Consecutive patients filled out the ASTA questionnaire, assessing symptoms, HRQoL, and perception of arrhythmia, prior to ablation. Patients were recruited from four Swedish and one Danish tertiary center. Results: A total of 2493 patients (72% men) filled out the ASTA questionnaire. Women experienced eight of the nine ASTA scale symptoms more often than men. Patients <65 years reported four symptoms more often, only tiredness was more frequent in those ≥65 years (P =.007). Women and patients <65 years experienced more often palpitations and regarding close to fainting and this was more common among women, no age differences were seen. Women and men scored differently in 10 of the 13 HRQoL items. Only negative impact on sexual life was more common in men (P <.001). Older patients reported more negative influence in four of the HRQoL items and the younger in one; ability to concentrate. Conclusions: Women experienced a more pronounced symptom burden and were more negatively affected in all HRQoL concerns, except for the negative impact on sexual life, where men reported more influence of AF. Differences between age groups were less pronounced. Disease-specific patient-reported outcomes measures (PROMs) add important information where gender differences should be considered in the care.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
age, atrial fibrillation, disease-specific questionnaire, gender, health-related quality of life, symptoms
in
PACE - Pacing and Clinical Electrophysiology
volume
42
issue
11
pages
9 pages
publisher
Wiley-Blackwell
external identifiers
  • pmid:31495941
  • scopus:85074241920
ISSN
0147-8389
DOI
10.1111/pace.13795
language
English
LU publication?
yes
id
4e70039e-f0f5-4643-b8f9-b020ad72b415
date added to LUP
2019-11-15 12:20:18
date last changed
2022-05-11 22:54:50
@article{4e70039e-f0f5-4643-b8f9-b020ad72b415,
  abstract     = {{<p>Background: Primary indication for catheter ablation of atrial fibrillation (AF) is to reduce symptoms and improve health-related quality of life (HRQoL). There are data showing differences between the genders and between younger and older patients. To evaluate this, we studied a large Scandinavian cohort of patients referred for catheter ablation of AF. Methods: Consecutive patients filled out the ASTA questionnaire, assessing symptoms, HRQoL, and perception of arrhythmia, prior to ablation. Patients were recruited from four Swedish and one Danish tertiary center. Results: A total of 2493 patients (72% men) filled out the ASTA questionnaire. Women experienced eight of the nine ASTA scale symptoms more often than men. Patients &lt;65 years reported four symptoms more often, only tiredness was more frequent in those ≥65 years (P =.007). Women and patients &lt;65 years experienced more often palpitations and regarding close to fainting and this was more common among women, no age differences were seen. Women and men scored differently in 10 of the 13 HRQoL items. Only negative impact on sexual life was more common in men (P &lt;.001). Older patients reported more negative influence in four of the HRQoL items and the younger in one; ability to concentrate. Conclusions: Women experienced a more pronounced symptom burden and were more negatively affected in all HRQoL concerns, except for the negative impact on sexual life, where men reported more influence of AF. Differences between age groups were less pronounced. Disease-specific patient-reported outcomes measures (PROMs) add important information where gender differences should be considered in the care.</p>}},
  author       = {{Walfridsson, Ulla and Steen Hansen, Peter and Charitakis, Emmanouil and Almroth, Henrik and Jönsson, Anders and Karlsson, Lars O. and Liuba, Ioan and Samo Ayou, Romeo and Poci, Dritan and Holmqvist, Fredrik and Kongstad, Ole and Walfridsson, Håkan}},
  issn         = {{0147-8389}},
  keywords     = {{age; atrial fibrillation; disease-specific questionnaire; gender; health-related quality of life; symptoms}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{1431--1439}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{PACE - Pacing and Clinical Electrophysiology}},
  title        = {{Gender and age differences in symptoms and health-related quality of life in patients with atrial fibrillation referred for catheter ablation}},
  url          = {{http://dx.doi.org/10.1111/pace.13795}},
  doi          = {{10.1111/pace.13795}},
  volume       = {{42}},
  year         = {{2019}},
}