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How vitamins act as novel agents for ameliorating diabetic peripheral neuropathy : A comprehensive overview

Li, Kezheng ; Chen, Yinuo ; Xie, Jiali ; Cai, Weiwei ; Pang, Chunyang ; Cui, Can ; Huan, Yu and Deng, Binbin (2023) In Ageing Research Reviews 91.
Abstract

Diabetic peripheral neuropathy (DPN) is a pervasive and incapacitating sequela of diabetes, affecting a significant proportion of those diagnosed with the disease, yet an effective treatment remains elusive. Vitamins have been extensively studied, emerging as a promising target for diagnosing and treating various systemic diseases, but their role in DPN is not known. This review collates and synthesizes knowledge regarding the interplay between vitamins and DPN, drawing on bibliographies from prior studies and relevant articles, and stratifying the therapeutic strategies from prophylactic to interventional. In addition, the clinical evidence supporting the use of vitamins to ameliorate DPN is also evaluated, underscoring the potential... (More)

Diabetic peripheral neuropathy (DPN) is a pervasive and incapacitating sequela of diabetes, affecting a significant proportion of those diagnosed with the disease, yet an effective treatment remains elusive. Vitamins have been extensively studied, emerging as a promising target for diagnosing and treating various systemic diseases, but their role in DPN is not known. This review collates and synthesizes knowledge regarding the interplay between vitamins and DPN, drawing on bibliographies from prior studies and relevant articles, and stratifying the therapeutic strategies from prophylactic to interventional. In addition, the clinical evidence supporting the use of vitamins to ameliorate DPN is also evaluated, underscoring the potential of vitamins as putative therapeutic agents. We anticipate that this review will offer novel insights for developing and applying vitamin-based therapies for DPN.

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author
; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Aspects of diabetes, Peripheral neuropathy, Vitamin B Group, Vitamin C, Vitamin D
in
Ageing Research Reviews
volume
91
article number
102064
publisher
Elsevier
external identifiers
  • pmid:37689144
  • scopus:85170570620
ISSN
1568-1637
DOI
10.1016/j.arr.2023.102064
language
English
LU publication?
no
id
4f198ea7-9e01-4a56-970b-97f2e63078d8
date added to LUP
2023-12-05 15:21:57
date last changed
2024-04-18 11:07:36
@article{4f198ea7-9e01-4a56-970b-97f2e63078d8,
  abstract     = {{<p>Diabetic peripheral neuropathy (DPN) is a pervasive and incapacitating sequela of diabetes, affecting a significant proportion of those diagnosed with the disease, yet an effective treatment remains elusive. Vitamins have been extensively studied, emerging as a promising target for diagnosing and treating various systemic diseases, but their role in DPN is not known. This review collates and synthesizes knowledge regarding the interplay between vitamins and DPN, drawing on bibliographies from prior studies and relevant articles, and stratifying the therapeutic strategies from prophylactic to interventional. In addition, the clinical evidence supporting the use of vitamins to ameliorate DPN is also evaluated, underscoring the potential of vitamins as putative therapeutic agents. We anticipate that this review will offer novel insights for developing and applying vitamin-based therapies for DPN.</p>}},
  author       = {{Li, Kezheng and Chen, Yinuo and Xie, Jiali and Cai, Weiwei and Pang, Chunyang and Cui, Can and Huan, Yu and Deng, Binbin}},
  issn         = {{1568-1637}},
  keywords     = {{Aspects of diabetes; Peripheral neuropathy; Vitamin B Group; Vitamin C; Vitamin D}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Ageing Research Reviews}},
  title        = {{How vitamins act as novel agents for ameliorating diabetic peripheral neuropathy : A comprehensive overview}},
  url          = {{http://dx.doi.org/10.1016/j.arr.2023.102064}},
  doi          = {{10.1016/j.arr.2023.102064}},
  volume       = {{91}},
  year         = {{2023}},
}