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Pseudomyxoma peritonei : A review of 62 cases

van Ruth, S. ; Acherman, Y. I.Z. ; van de Vijver, M. J. ; Hart, A. A.M. ; Verwaal, V. J. LU and Zoetmulder, F. A.N. (2003) In European Journal of Surgical Oncology 29(8). p.682-688
Abstract

Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than... (More)

Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than those with more focal proliferation (n = 14). Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Disseminated peritoneal adenomucinosis, HIPEC, Pathology, Peritoneal mucinous carcinomatosis with intermediate or discordant features, Pseudomyxoma peritonei
in
European Journal of Surgical Oncology
volume
29
issue
8
pages
682 - 688
publisher
Elsevier
external identifiers
  • scopus:0141954881
  • pmid:14511618
ISSN
0748-7983
DOI
10.1016/S0748-7983(03)00149-5
language
English
LU publication?
no
id
4f3d4c7b-1e73-435f-b249-42a62804574e
date added to LUP
2022-04-12 11:10:39
date last changed
2025-04-08 05:24:02
@article{4f3d4c7b-1e73-435f-b249-42a62804574e,
  abstract     = {{<p>Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than those with more focal proliferation (n = 14). Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.</p>}},
  author       = {{van Ruth, S. and Acherman, Y. I.Z. and van de Vijver, M. J. and Hart, A. A.M. and Verwaal, V. J. and Zoetmulder, F. A.N.}},
  issn         = {{0748-7983}},
  keywords     = {{Disseminated peritoneal adenomucinosis; HIPEC; Pathology; Peritoneal mucinous carcinomatosis with intermediate or discordant features; Pseudomyxoma peritonei}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{682--688}},
  publisher    = {{Elsevier}},
  series       = {{European Journal of Surgical Oncology}},
  title        = {{Pseudomyxoma peritonei : A review of 62 cases}},
  url          = {{http://dx.doi.org/10.1016/S0748-7983(03)00149-5}},
  doi          = {{10.1016/S0748-7983(03)00149-5}},
  volume       = {{29}},
  year         = {{2003}},
}