Laboratory investigation of myeloproliferative neoplasms (MPNs) : Recommendations of the Canadian MPN group
(2016) In American Journal of Clinical Pathology 146(4). p.408-422- Abstract
Objectives: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. Methods: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing treatment guidelines, and availability of diagnostic tools. Each group member was assigned a specific topic, which they discussed with the entire group during several consensus meetings. Results: This document provides the Canadian MPN group's recommendations, proposed diagnostic algorithms, and background evidence upon which decisions were... (More)
Objectives: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. Methods: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing treatment guidelines, and availability of diagnostic tools. Each group member was assigned a specific topic, which they discussed with the entire group during several consensus meetings. Results: This document provides the Canadian MPN group's recommendations, proposed diagnostic algorithms, and background evidence upon which decisions were made. Conclusions: Standardization of diagnostic investigations will increase homogeneity in patient care and provide a foundation for future clinical research in this rapidly evolving therapeutic area. Streamlining diagnostic approaches in the most efficient and cost-effective manner will also result in significant cost saving for the health care system.
(Less)
- author
- publishing date
- 2016-09-23
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- BCR-ABL negative, CALR, Essential thrombocythemia, JAK2 V617F, MPL, Myelofibrosis, Myeloproliferative neoplasms, Polycythemia vera
- in
- American Journal of Clinical Pathology
- volume
- 146
- issue
- 4
- pages
- 15 pages
- publisher
- Oxford University Press
- external identifiers
-
- pmid:27686169
- scopus:85014118383
- ISSN
- 0002-9173
- DOI
- 10.1093/ajcp/aqw131
- language
- English
- LU publication?
- no
- id
- 4fcae6ad-a4db-4e50-8723-d11ac12c53e4
- date added to LUP
- 2019-05-22 09:38:16
- date last changed
- 2024-04-16 07:13:08
@article{4fcae6ad-a4db-4e50-8723-d11ac12c53e4, abstract = {{<p>Objectives: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. Methods: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing treatment guidelines, and availability of diagnostic tools. Each group member was assigned a specific topic, which they discussed with the entire group during several consensus meetings. Results: This document provides the Canadian MPN group's recommendations, proposed diagnostic algorithms, and background evidence upon which decisions were made. Conclusions: Standardization of diagnostic investigations will increase homogeneity in patient care and provide a foundation for future clinical research in this rapidly evolving therapeutic area. Streamlining diagnostic approaches in the most efficient and cost-effective manner will also result in significant cost saving for the health care system.</p>}}, author = {{Busque, Lambert and Porwit, Anna and Day, Radmila and Olney, Harold J. and Leber, Brian and Éthier, Vincent and Sirhan, Shireen and Foltz, Linda and Prchal, Jaroslav and Kamel-Reid, Suzanne and Karsan, Aly and Gupta, Vikas}}, issn = {{0002-9173}}, keywords = {{BCR-ABL negative; CALR; Essential thrombocythemia; JAK2 V617F; MPL; Myelofibrosis; Myeloproliferative neoplasms; Polycythemia vera}}, language = {{eng}}, month = {{09}}, number = {{4}}, pages = {{408--422}}, publisher = {{Oxford University Press}}, series = {{American Journal of Clinical Pathology}}, title = {{Laboratory investigation of myeloproliferative neoplasms (MPNs) : Recommendations of the Canadian MPN group}}, url = {{http://dx.doi.org/10.1093/ajcp/aqw131}}, doi = {{10.1093/ajcp/aqw131}}, volume = {{146}}, year = {{2016}}, }