Validation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia
(2006) In Japanese Journal of Infectious Diseases 59(6). p.90-388- Abstract
The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumoniae antigen test. The urinary antigen test was positive in 9 (15.3%) of 59 patients enrolled in the study and in 8 (73%) of 11 patients with pneumococcal pneumonia confirmed by conventional methods. The test revealed a sensitivity of 72.7% and a specificity of 97.6% with conventional microbiological criteria used as the reference standard. The... (More)
The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumoniae antigen test. The urinary antigen test was positive in 9 (15.3%) of 59 patients enrolled in the study and in 8 (73%) of 11 patients with pneumococcal pneumonia confirmed by conventional methods. The test revealed a sensitivity of 72.7% and a specificity of 97.6% with conventional microbiological criteria used as the reference standard. The positive predictive value was 88.9% and the negative predictive value was 93%. We concluded that the urinary antigen test can supplement conventional microbiological tests in the diagnosis of pneumococcal pneumonia.
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- author
- Ercis, Serpil ; Ergin, Alper ; Sahin, Gülşen Ozkaya LU ; Hasçelik, Gülşen and Uzun, Omrüm
- publishing date
- 2006-12
- type
- Contribution to journal
- publication status
- published
- keywords
- Adolescent, Adult, Aged, Aged, 80 and over, Antigens, Bacterial/urine, Female, Humans, Male, Middle Aged, Pneumonia, Pneumococcal/diagnosis, Predictive Value of Tests, Sensitivity and Specificity, Streptococcus pneumoniae/immunology
- in
- Japanese Journal of Infectious Diseases
- volume
- 59
- issue
- 6
- pages
- 3 pages
- publisher
- National Institute of Infectious Diseases. (Tokyo)
- external identifiers
-
- scopus:33845972978
- pmid:17186959
- ISSN
- 1344-6304
- language
- English
- LU publication?
- no
- id
- 4fe77655-f3c4-4f01-92bd-df6c002106ae
- alternative location
- http://www0.nih.go.jp/JJID/59/388.html
- date added to LUP
- 2019-06-30 00:58:38
- date last changed
- 2024-01-01 14:29:04
@article{4fe77655-f3c4-4f01-92bd-df6c002106ae,
abstract = {{<p>The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumoniae antigen test. The urinary antigen test was positive in 9 (15.3%) of 59 patients enrolled in the study and in 8 (73%) of 11 patients with pneumococcal pneumonia confirmed by conventional methods. The test revealed a sensitivity of 72.7% and a specificity of 97.6% with conventional microbiological criteria used as the reference standard. The positive predictive value was 88.9% and the negative predictive value was 93%. We concluded that the urinary antigen test can supplement conventional microbiological tests in the diagnosis of pneumococcal pneumonia.</p>}},
author = {{Ercis, Serpil and Ergin, Alper and Sahin, Gülşen Ozkaya and Hasçelik, Gülşen and Uzun, Omrüm}},
issn = {{1344-6304}},
keywords = {{Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Bacterial/urine; Female; Humans; Male; Middle Aged; Pneumonia, Pneumococcal/diagnosis; Predictive Value of Tests; Sensitivity and Specificity; Streptococcus pneumoniae/immunology}},
language = {{eng}},
number = {{6}},
pages = {{90--388}},
publisher = {{National Institute of Infectious Diseases. (Tokyo)}},
series = {{Japanese Journal of Infectious Diseases}},
title = {{Validation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia}},
url = {{http://www0.nih.go.jp/JJID/59/388.html}},
volume = {{59}},
year = {{2006}},
}