The human antibody repertoire to infectious agents: implications for disease pathogenesis
Ohlin, Mats LU
and Zouali, Moncef
(2003)
In Molecular Immunology
40(1).
p.1-11
- Abstract
- Antibodies are critical entities used for the protection of an individual organism against infection and disease. Through a complex series of events genes rearrange to encode repertoires of molecules, which are tested for their ability to identify foreign molecules. In this report, we discuss factors defined by the individual as well as by infectious organisms that shape the antibody repertoire. A more thorough understanding of the interplay between these factors will eventually allow us to elucidate the underlying mechanisms of disease susceptibility following infection, and to design potent vaccines and other immunomodulating reagents.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/134316
- author
- Ohlin, Mats
LU
and Zouali, Moncef
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Molecular Immunology
- volume
- 40
- issue
- 1
- pages
- 1 - 11
- publisher
- Pergamon Press Ltd.
- external identifiers
-
- pmid:12909126
- wos:000184975700001
- scopus:0042697222
- ISSN
- 1872-9142
- DOI
- 10.1016/S0161-5890(03)00099-3
- language
- English
- LU publication?
- yes
- id
- 500a98df-c429-4941-8593-f43752cc5751 (old id 134316)
- date added to LUP
- 2016-04-01 16:49:35
- date last changed
- 2022-01-28 22:28:30
@article{500a98df-c429-4941-8593-f43752cc5751,
abstract = {{Antibodies are critical entities used for the protection of an individual organism against infection and disease. Through a complex series of events genes rearrange to encode repertoires of molecules, which are tested for their ability to identify foreign molecules. In this report, we discuss factors defined by the individual as well as by infectious organisms that shape the antibody repertoire. A more thorough understanding of the interplay between these factors will eventually allow us to elucidate the underlying mechanisms of disease susceptibility following infection, and to design potent vaccines and other immunomodulating reagents.}},
author = {{Ohlin, Mats and Zouali, Moncef}},
issn = {{1872-9142}},
language = {{eng}},
number = {{1}},
pages = {{1--11}},
publisher = {{Pergamon Press Ltd.}},
series = {{Molecular Immunology}},
title = {{The human antibody repertoire to infectious agents: implications for disease pathogenesis}},
url = {{http://dx.doi.org/10.1016/S0161-5890(03)00099-3}},
doi = {{10.1016/S0161-5890(03)00099-3}},
volume = {{40}},
year = {{2003}},
}