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Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.

Thomas, Owain LU ; Lybeck, Emanuel LU ; Strandberg, Karin LU ; Tynngård, Nahreen and Schött, Ulf LU (2015) In PLoS ONE 10(1).
Abstract
Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
10
issue
1
publisher
Public Library of Science
external identifiers
  • pmid:25625201
  • wos:000348821400018
  • scopus:84921969922
ISSN
1932-6203
DOI
10.1371/journal.pone.0116835
language
English
LU publication?
yes
id
8e2ba9de-9387-4a07-8d65-3dc0a76955c1 (old id 5039555)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25625201?dopt=Abstract
date added to LUP
2015-02-04 18:09:07
date last changed
2017-10-29 03:50:08
@article{8e2ba9de-9387-4a07-8d65-3dc0a76955c1,
  abstract     = {Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.},
  articleno    = {e0116835},
  author       = {Thomas, Owain and Lybeck, Emanuel and Strandberg, Karin and Tynngård, Nahreen and Schött, Ulf},
  issn         = {1932-6203},
  language     = {eng},
  number       = {1},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0116835},
  volume       = {10},
  year         = {2015},
}