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Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.

Foroughi Asl, Hassan; Talukdar, Husain A; Kindt, Alida S D; Jain, Rajeev K; Ermel, Raili; Ruusalepp, Arno; Nguyen, Khanh-Dung H; Dobrin, Radu; Reilly, Dermot F and Schunkert, Heribert, et al. (2015) In Circulation: Cardiovascular Genetics 8(2). p.305-305
Abstract
-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.
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Contribution to journal
publication status
published
subject
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Circulation: Cardiovascular Genetics
volume
8
issue
2
pages
305 - 305
publisher
American Heart Association
external identifiers
  • pmid:25578447
  • wos:000353309600009
  • scopus:84923328349
ISSN
1942-325X
DOI
10.1161/CIRCGENETICS.114.000640
language
English
LU publication?
yes
id
071f1543-c8eb-43c9-8fec-62e32c3ff83b (old id 5040798)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25578447?dopt=Abstract
date added to LUP
2015-02-02 21:34:29
date last changed
2017-11-05 03:03:40
@article{071f1543-c8eb-43c9-8fec-62e32c3ff83b,
  abstract     = {-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.},
  author       = {Foroughi Asl, Hassan and Talukdar, Husain A and Kindt, Alida S D and Jain, Rajeev K and Ermel, Raili and Ruusalepp, Arno and Nguyen, Khanh-Dung H and Dobrin, Radu and Reilly, Dermot F and Schunkert, Heribert and Samani, Nilesh J and Brænne, Ingrid and Erdmann, Jeanette and Melander, Olle and Qi, Jianlong and Ivert, Torbjörn and Skogsberg, Josefin and Schadt, Eric E and Michoel, Tom and Björkegren, Johan L M},
  issn         = {1942-325X},
  language     = {eng},
  number       = {2},
  pages        = {305--305},
  publisher    = {American Heart Association},
  series       = {Circulation: Cardiovascular Genetics},
  title        = {Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.},
  url          = {http://dx.doi.org/10.1161/CIRCGENETICS.114.000640},
  volume       = {8},
  year         = {2015},
}