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Environmental proxies of antigen exposure explain variation in immune investment better than indices of pace of life

Nicholas P.C., Horrocks; Hegemann, Arne LU ; Stephan, Ostrowski; Henry, Nidithia; Mohammed, Shobrak; Joseph B., Williams; Kevin D., Matson and B. Irene, Tieleman (2015) In Oecologia 177(1). p.281-290
Abstract
Investment in immune defences is predicted to covary with a variety of ecologically and evolutionarily relevant axes, with pace of life and environmental antigen exposure being two examples. These axes may themselves covary directly or inversely, and such relationships can lead to conflicting predictions regarding immune investment. If pace of life shapes immune investment then, following life history theory, slow-living, arid zone and tropical species should invest more in immunity than fast-living temperate species. Alternatively, if antigen exposure drives immune investment, then species in antigen-rich tropical and temperate environments are predicted to exhibit higher immune indices than species from antigen-poor arid locations. To... (More)
Investment in immune defences is predicted to covary with a variety of ecologically and evolutionarily relevant axes, with pace of life and environmental antigen exposure being two examples. These axes may themselves covary directly or inversely, and such relationships can lead to conflicting predictions regarding immune investment. If pace of life shapes immune investment then, following life history theory, slow-living, arid zone and tropical species should invest more in immunity than fast-living temperate species. Alternatively, if antigen exposure drives immune investment, then species in antigen-rich tropical and temperate environments are predicted to exhibit higher immune indices than species from antigen-poor arid locations. To test these contrasting predictions we investigated how variation in pace of life and antigen exposure influence immune investment in related lark species (Alaudidae) with differing life histories and predicted risks of exposure to environmental microbes and parasites. We used clutch size and total number of eggs laid per year as indicators of pace of life, and aridity, and the climatic variables that influence aridity, as correlates of antigen abundance. We quantified immune investment by measuring four indices of innate immunity. Pace of life explained little of the variation in immune investment, and only one immune measure correlated significantly with pace of life, but not in the predicted direction. Conversely, aridity, our proxy for environmental antigen exposure, was predictive of immune investment, and larks in more mesic environments had higher immune indices than those living in arid, low-risk locations. Our study suggests that abiotic environmental variables with strong ties to environmental antigen exposure can be important correlates of immunological variation. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Oecologia
volume
177
issue
1
pages
281 - 290
publisher
Springer
external identifiers
  • scopus:84929442393
ISSN
1432-1939
DOI
10.1007/s00442-014-3136-y
language
English
LU publication?
yes
id
1123ad0c-19c7-47bd-a943-d0cd9a1774c0 (old id 5051907)
date added to LUP
2015-02-26 13:43:46
date last changed
2017-09-17 06:51:02
@article{1123ad0c-19c7-47bd-a943-d0cd9a1774c0,
  abstract     = {Investment in immune defences is predicted to covary with a variety of ecologically and evolutionarily relevant axes, with pace of life and environmental antigen exposure being two examples. These axes may themselves covary directly or inversely, and such relationships can lead to conflicting predictions regarding immune investment. If pace of life shapes immune investment then, following life history theory, slow-living, arid zone and tropical species should invest more in immunity than fast-living temperate species. Alternatively, if antigen exposure drives immune investment, then species in antigen-rich tropical and temperate environments are predicted to exhibit higher immune indices than species from antigen-poor arid locations. To test these contrasting predictions we investigated how variation in pace of life and antigen exposure influence immune investment in related lark species (Alaudidae) with differing life histories and predicted risks of exposure to environmental microbes and parasites. We used clutch size and total number of eggs laid per year as indicators of pace of life, and aridity, and the climatic variables that influence aridity, as correlates of antigen abundance. We quantified immune investment by measuring four indices of innate immunity. Pace of life explained little of the variation in immune investment, and only one immune measure correlated significantly with pace of life, but not in the predicted direction. Conversely, aridity, our proxy for environmental antigen exposure, was predictive of immune investment, and larks in more mesic environments had higher immune indices than those living in arid, low-risk locations. Our study suggests that abiotic environmental variables with strong ties to environmental antigen exposure can be important correlates of immunological variation.},
  author       = {Nicholas P.C., Horrocks and Hegemann, Arne and Stephan, Ostrowski and Henry, Nidithia and Mohammed, Shobrak and Joseph B., Williams and Kevin D., Matson and B. Irene, Tieleman},
  issn         = {1432-1939},
  language     = {eng},
  number       = {1},
  pages        = {281--290},
  publisher    = {Springer},
  series       = {Oecologia},
  title        = {Environmental proxies of antigen exposure explain variation in immune investment better than indices of pace of life},
  url          = {http://dx.doi.org/10.1007/s00442-014-3136-y},
  volume       = {177},
  year         = {2015},
}