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The level of physical exercise is associated with self-reported health status (EQ-5D) in adults with congenital heart disease

Sandberg, Camilla; Engstrom, Karl Gunnar; Dellborg, Mikael; Thilén, Ulf LU ; Wadell, Karin and Johansson, Bengt (2015) In European Journal of Preventive Cardiology 22(2). p.240-248
Abstract
Background The prognosis in adults with congenital aortic valve disease is usually favourable; nevertheless, a number of medical and social factors might hamper long-term prognosis and quality of life. With a focus on physical exercise level, data from the Swedish National Registry on Congenital Heart Disease (SWEDCON) were analysed and variables associated with health-related quality of life in adults with congenital aortic valve disease were identified. Methods In this registry study, SWEDCON was searched for adult patients with isolated congenital aortic valve disease and valid EuroQol-5Dimensions health questionnaire (EQ-5D) data. Results This study identified 315 patients. The majority (n=202, 64%) reported best possible health status... (More)
Background The prognosis in adults with congenital aortic valve disease is usually favourable; nevertheless, a number of medical and social factors might hamper long-term prognosis and quality of life. With a focus on physical exercise level, data from the Swedish National Registry on Congenital Heart Disease (SWEDCON) were analysed and variables associated with health-related quality of life in adults with congenital aortic valve disease were identified. Methods In this registry study, SWEDCON was searched for adult patients with isolated congenital aortic valve disease and valid EuroQol-5Dimensions health questionnaire (EQ-5D) data. Results This study identified 315 patients. The majority (n=202, 64%) reported best possible health status (EQ-5D(index)=1) whereas 113 (35%) reported some impairment (EQ-5D(index)<1) with mean EQ-5D(index) 0.730.17. In a multivariate logistic regression model, self-reported physical exercise>3h/week was independently associated with best possible health status (EQ-5D(index)=1; p=0.013). Moreover presence of cardiovascular symptoms (p<0.001), active smoking (p=0.002), history of valve surgery (p=0.017), low educational level (p=0.022), and higher systolic blood pressure (p=0.029) were independently associated with impaired health status (EQ-5D(index)<1). Conclusions Physical exercise >3h/week was, as a single variable, associated with best possible health status in adults with congenital aortic valve disease. In contrast, a number of medical and social factors are associated with worse self-reported health status. Among these, symptoms, smoking, and educational level are potential targets for modification and intervention. There is a need for studies investigating the effect of increased level of physical exercise in patients with congenital aortic valve disease. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult congenital heart disease, aortic regurgitation, aortic stenosis, bicuspid aortic valve, EQ-5D
in
European Journal of Preventive Cardiology
volume
22
issue
2
pages
240 - 248
publisher
SAGE Publications Inc.
external identifiers
  • wos:000348115400015
  • scopus:84920996038
ISSN
2047-4881
DOI
10.1177/2047487313508665
language
English
LU publication?
yes
id
43df9fb9-8422-4894-bf28-7a2e65e7dbdb (old id 5053333)
date added to LUP
2015-03-02 07:14:23
date last changed
2017-01-01 05:44:42
@article{43df9fb9-8422-4894-bf28-7a2e65e7dbdb,
  abstract     = {Background The prognosis in adults with congenital aortic valve disease is usually favourable; nevertheless, a number of medical and social factors might hamper long-term prognosis and quality of life. With a focus on physical exercise level, data from the Swedish National Registry on Congenital Heart Disease (SWEDCON) were analysed and variables associated with health-related quality of life in adults with congenital aortic valve disease were identified. Methods In this registry study, SWEDCON was searched for adult patients with isolated congenital aortic valve disease and valid EuroQol-5Dimensions health questionnaire (EQ-5D) data. Results This study identified 315 patients. The majority (n=202, 64%) reported best possible health status (EQ-5D(index)=1) whereas 113 (35%) reported some impairment (EQ-5D(index)&lt;1) with mean EQ-5D(index) 0.730.17. In a multivariate logistic regression model, self-reported physical exercise&gt;3h/week was independently associated with best possible health status (EQ-5D(index)=1; p=0.013). Moreover presence of cardiovascular symptoms (p&lt;0.001), active smoking (p=0.002), history of valve surgery (p=0.017), low educational level (p=0.022), and higher systolic blood pressure (p=0.029) were independently associated with impaired health status (EQ-5D(index)&lt;1). Conclusions Physical exercise &gt;3h/week was, as a single variable, associated with best possible health status in adults with congenital aortic valve disease. In contrast, a number of medical and social factors are associated with worse self-reported health status. Among these, symptoms, smoking, and educational level are potential targets for modification and intervention. There is a need for studies investigating the effect of increased level of physical exercise in patients with congenital aortic valve disease.},
  author       = {Sandberg, Camilla and Engstrom, Karl Gunnar and Dellborg, Mikael and Thilén, Ulf and Wadell, Karin and Johansson, Bengt},
  issn         = {2047-4881},
  keyword      = {Adult congenital heart disease,aortic regurgitation,aortic stenosis,bicuspid aortic valve,EQ-5D},
  language     = {eng},
  number       = {2},
  pages        = {240--248},
  publisher    = {SAGE Publications Inc.},
  series       = {European Journal of Preventive Cardiology},
  title        = {The level of physical exercise is associated with self-reported health status (EQ-5D) in adults with congenital heart disease},
  url          = {http://dx.doi.org/10.1177/2047487313508665},
  volume       = {22},
  year         = {2015},
}