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Etiological factors in acute appendicitis, an experimental study using the human appendix transplant

Arnbjornsson, E. LU (1987) In Surgical Research Communications 1(4). p.289-291
Abstract

In an experimental model using the human appendix transplanted into the Rowett rat, the role of obstruction in the pathogenesis of acute appendicitis was studied. Nine animals were anaesthetized and underwent laparotomy. Normal human appendices, removed during routine surgery, were transplanted into the rats. The appendices were obstructed by a balloon catheter introduced through the open end. Pressure inside the obstructed appendices was measured with a balloon at the tip of the catheter. The anaesthesia was continued and pressures were registered regularly up to six hours afterwards. The animals were then sacrificed. At autopsy the appendix was studied and evidence of obstruction, distention and inflammatory changes, both gross and... (More)

In an experimental model using the human appendix transplanted into the Rowett rat, the role of obstruction in the pathogenesis of acute appendicitis was studied. Nine animals were anaesthetized and underwent laparotomy. Normal human appendices, removed during routine surgery, were transplanted into the rats. The appendices were obstructed by a balloon catheter introduced through the open end. Pressure inside the obstructed appendices was measured with a balloon at the tip of the catheter. The anaesthesia was continued and pressures were registered regularly up to six hours afterwards. The animals were then sacrificed. At autopsy the appendix was studied and evidence of obstruction, distention and inflammatory changes, both gross and microscopic, was registered.

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author
organization
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type
Contribution to journal
publication status
published
in
Surgical Research Communications
volume
1
issue
4
pages
3 pages
publisher
M. Gordan and Breach - Harwood Academic
external identifiers
  • scopus:0023473403
ISSN
0882-9233
language
English
LU publication?
yes
id
50561a23-e3ce-4dec-a9c7-d1e443f99a66
date added to LUP
2018-11-09 09:55:34
date last changed
2019-01-06 14:14:10
@article{50561a23-e3ce-4dec-a9c7-d1e443f99a66,
  abstract     = {<p>In an experimental model using the human appendix transplanted into the Rowett rat, the role of obstruction in the pathogenesis of acute appendicitis was studied. Nine animals were anaesthetized and underwent laparotomy. Normal human appendices, removed during routine surgery, were transplanted into the rats. The appendices were obstructed by a balloon catheter introduced through the open end. Pressure inside the obstructed appendices was measured with a balloon at the tip of the catheter. The anaesthesia was continued and pressures were registered regularly up to six hours afterwards. The animals were then sacrificed. At autopsy the appendix was studied and evidence of obstruction, distention and inflammatory changes, both gross and microscopic, was registered.</p>},
  author       = {Arnbjornsson, E.},
  issn         = {0882-9233},
  language     = {eng},
  month        = {01},
  number       = {4},
  pages        = {289--291},
  publisher    = {M. Gordan and Breach - Harwood Academic},
  series       = {Surgical Research Communications},
  title        = {Etiological factors in acute appendicitis, an experimental study using the human appendix transplant},
  volume       = {1},
  year         = {1987},
}