Characterization of a double-sided silicon strip detector autoradiography system.
(2015) In Medical Physics 42(2). p.575-584- Abstract
- The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this study is to characterize the imaging performance of one such instrument, a double-sided silicon strip detector (DSSD) system for digital autoradiography. A novel aspect of this work is that the instrument, in contrast to previous prototype systems using the same detector type, provides the ability for user accessible imaging with higher throughput.... (More)
- The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this study is to characterize the imaging performance of one such instrument, a double-sided silicon strip detector (DSSD) system for digital autoradiography. A novel aspect of this work is that the instrument, in contrast to previous prototype systems using the same detector type, provides the ability for user accessible imaging with higher throughput. Studies were performed to compare its spatial resolution to that of storage phosphor screens and test the implementation of multiradionuclide ex vivo imaging in a mouse preclinical animal study. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5145451
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Medical Physics
- volume
- 42
- issue
- 2
- pages
- 575 - 584
- publisher
- American Association of Physicists in Medicine
- external identifiers
-
- pmid:25652478
- wos:000349229600006
- scopus:84923346577
- pmid:25652478
- ISSN
- 0094-2405
- DOI
- 10.1118/1.4905049
- language
- English
- LU publication?
- yes
- id
- 35e8bb4e-96dd-41b9-8e38-647292186901 (old id 5145451)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25652478?dopt=Abstract
- date added to LUP
- 2016-04-01 15:06:24
- date last changed
- 2022-01-28 04:32:07
@article{35e8bb4e-96dd-41b9-8e38-647292186901, abstract = {{The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this study is to characterize the imaging performance of one such instrument, a double-sided silicon strip detector (DSSD) system for digital autoradiography. A novel aspect of this work is that the instrument, in contrast to previous prototype systems using the same detector type, provides the ability for user accessible imaging with higher throughput. Studies were performed to compare its spatial resolution to that of storage phosphor screens and test the implementation of multiradionuclide ex vivo imaging in a mouse preclinical animal study.}}, author = {{Örbom, Anders and Ahlstedt, Jonas and Serén, Tom and Auterinen, Iiro and Kotiluoto, Petri and Hauge, Håvard and Östlund, Karl and Olafsen, Tove and Wu, Anna M and Dahlbom, Magnus and Strand, Sven-Erik}}, issn = {{0094-2405}}, language = {{eng}}, number = {{2}}, pages = {{575--584}}, publisher = {{American Association of Physicists in Medicine}}, series = {{Medical Physics}}, title = {{Characterization of a double-sided silicon strip detector autoradiography system.}}, url = {{https://lup.lub.lu.se/search/files/4341293/7791835.pdf}}, doi = {{10.1118/1.4905049}}, volume = {{42}}, year = {{2015}}, }