Advanced

Characterization of a double-sided silicon strip detector autoradiography system.

Örbom, Anders LU ; Ahlstedt, Jonas LU ; Serén, Tom; Auterinen, Iiro; Kotiluoto, Petri; Hauge, Håvard; Östlund, Karl LU ; Olafsen, Tove; Wu, Anna M and Dahlbom, Magnus, et al. (2015) In Medical Physics 42(2). p.575-584
Abstract
The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this study is to characterize the imaging performance of one such instrument, a double-sided silicon strip detector (DSSD) system for digital autoradiography. A novel aspect of this work is that the instrument, in contrast to previous prototype systems using the same detector type, provides the ability for user accessible imaging with higher throughput.... (More)
The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this study is to characterize the imaging performance of one such instrument, a double-sided silicon strip detector (DSSD) system for digital autoradiography. A novel aspect of this work is that the instrument, in contrast to previous prototype systems using the same detector type, provides the ability for user accessible imaging with higher throughput. Studies were performed to compare its spatial resolution to that of storage phosphor screens and test the implementation of multiradionuclide ex vivo imaging in a mouse preclinical animal study. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Medical Physics
volume
42
issue
2
pages
575 - 584
publisher
American Association of Physicists in Medicine
external identifiers
  • pmid:25652478
  • wos:000349229600006
  • scopus:84923346577
ISSN
0094-2405
DOI
10.1118/1.4905049
language
English
LU publication?
yes
id
35e8bb4e-96dd-41b9-8e38-647292186901 (old id 5145451)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25652478?dopt=Abstract
date added to LUP
2015-03-04 15:16:32
date last changed
2017-01-01 06:36:11
@article{35e8bb4e-96dd-41b9-8e38-647292186901,
  abstract     = {The most commonly used technology currently used for autoradiography is storage phosphor screens, which has many benefits such as a large field of view but lacks particle-counting detection of the time and energy of each detected radionuclide decay. A number of alternative designs, using either solid state or scintillator detectors, have been developed to address these issues. The aim of this study is to characterize the imaging performance of one such instrument, a double-sided silicon strip detector (DSSD) system for digital autoradiography. A novel aspect of this work is that the instrument, in contrast to previous prototype systems using the same detector type, provides the ability for user accessible imaging with higher throughput. Studies were performed to compare its spatial resolution to that of storage phosphor screens and test the implementation of multiradionuclide ex vivo imaging in a mouse preclinical animal study.},
  author       = {Örbom, Anders and Ahlstedt, Jonas and Serén, Tom and Auterinen, Iiro and Kotiluoto, Petri and Hauge, Håvard and Östlund, Karl and Olafsen, Tove and Wu, Anna M and Dahlbom, Magnus and Strand, Sven-Erik},
  issn         = {0094-2405},
  language     = {eng},
  number       = {2},
  pages        = {575--584},
  publisher    = {American Association of Physicists in Medicine},
  series       = {Medical Physics},
  title        = {Characterization of a double-sided silicon strip detector autoradiography system.},
  url          = {http://dx.doi.org/10.1118/1.4905049},
  volume       = {42},
  year         = {2015},
}