Prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients in general practice: a cross-sectional study based on French and Italian prescribing data
(2015) In BMC Family Practice 16.- Abstract
- Background: Asthma is often poorly controlled and guidelines are often inadequately followed in medical practice. In particular, the prescription of non-asthma-specific drugs can affect the quality of care. The goal of this study was to measure the frequency of the prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients and to look for associations between sex or age and the prescription of these drugs. Methods: A cross-sectional study was conducted using computerised medical records from French and Italian general practitioners' networks. Patients were selected according to criteria adapted from the HEDIS (Healthcare Effectiveness Data and Information Set) criteria. The outcome measure was the number of antibiotics or... (More)
- Background: Asthma is often poorly controlled and guidelines are often inadequately followed in medical practice. In particular, the prescription of non-asthma-specific drugs can affect the quality of care. The goal of this study was to measure the frequency of the prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients and to look for associations between sex or age and the prescription of these drugs. Methods: A cross-sectional study was conducted using computerised medical records from French and Italian general practitioners' networks. Patients were selected according to criteria adapted from the HEDIS (Healthcare Effectiveness Data and Information Set) criteria. The outcome measure was the number of antibiotics or anxiolytics/hypnotics prescriptions per patient in 1 year. Parallel multivariate models were developed. Results: The final sample included 3,093 French patients (mean age 27.6 years, 49.7% women) and 3,872 Italian patients (mean age 29.1 years, 48.7% women). In the univariate analysis, the French patients were prescribed fewer antibiotics than the Italian patients (37.1% vs. 42.2%, p < 0.00001) but more anxiolytics/hypnotics (17.8% vs. 6.9%, p < 0.0001). In the multivariate models, the female patients were more likely to receive antibiotics (odds ratio: 1.5 [1.3-1.7]) and anxiolytics/hypnotics (odds ratio: 1.8 [1.5-2.1]). Conclusions: The prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients is frequent, especially in women. Asthma guidelines should address this issue by referring to other guidelines covering the prescription of non-asthma-specific drugs, and alternative non-pharmacological interventions should be considered. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5186093
- author
- Darmon, David
; Laforest, Laurent
; Van Ganse, Eric
; Petrazzuoli, Ferdinando
LU
; van Weel, Chris and Letrilliart, Laurent
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Asthma, Antibiotics, Anxiolytics, Hypnotics, Drug prescription, Primary, care
- in
- BMC Family Practice
- volume
- 16
- article number
- 14
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000349343000001
- scopus:84923876994
- pmid:25655671
- ISSN
- 1471-2296
- DOI
- 10.1186/s12875-015-0222-0
- language
- English
- LU publication?
- yes
- id
- db62ce63-e60d-4962-945d-ab39bd010c26 (old id 5186093)
- date added to LUP
- 2016-04-01 13:49:26
- date last changed
- 2022-02-11 23:16:18
@article{db62ce63-e60d-4962-945d-ab39bd010c26, abstract = {{Background: Asthma is often poorly controlled and guidelines are often inadequately followed in medical practice. In particular, the prescription of non-asthma-specific drugs can affect the quality of care. The goal of this study was to measure the frequency of the prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients and to look for associations between sex or age and the prescription of these drugs. Methods: A cross-sectional study was conducted using computerised medical records from French and Italian general practitioners' networks. Patients were selected according to criteria adapted from the HEDIS (Healthcare Effectiveness Data and Information Set) criteria. The outcome measure was the number of antibiotics or anxiolytics/hypnotics prescriptions per patient in 1 year. Parallel multivariate models were developed. Results: The final sample included 3,093 French patients (mean age 27.6 years, 49.7% women) and 3,872 Italian patients (mean age 29.1 years, 48.7% women). In the univariate analysis, the French patients were prescribed fewer antibiotics than the Italian patients (37.1% vs. 42.2%, p < 0.00001) but more anxiolytics/hypnotics (17.8% vs. 6.9%, p < 0.0001). In the multivariate models, the female patients were more likely to receive antibiotics (odds ratio: 1.5 [1.3-1.7]) and anxiolytics/hypnotics (odds ratio: 1.8 [1.5-2.1]). Conclusions: The prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients is frequent, especially in women. Asthma guidelines should address this issue by referring to other guidelines covering the prescription of non-asthma-specific drugs, and alternative non-pharmacological interventions should be considered.}}, author = {{Darmon, David and Laforest, Laurent and Van Ganse, Eric and Petrazzuoli, Ferdinando and van Weel, Chris and Letrilliart, Laurent}}, issn = {{1471-2296}}, keywords = {{Asthma; Antibiotics; Anxiolytics; Hypnotics; Drug prescription; Primary; care}}, language = {{eng}}, publisher = {{BioMed Central (BMC)}}, series = {{BMC Family Practice}}, title = {{Prescription of antibiotics and anxiolytics/hypnotics to asthmatic patients in general practice: a cross-sectional study based on French and Italian prescribing data}}, url = {{https://lup.lub.lu.se/search/files/3611425/8053164}}, doi = {{10.1186/s12875-015-0222-0}}, volume = {{16}}, year = {{2015}}, }