Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
(2015) In The Lancet 385(9984). p.2264-2271- Abstract
- Genetic variants have been associated with the risk of coronary heart disease. In this study, we tested whether or not a composite of these variants could ascertain the risk of both incident and recurrent coronary heart disease events and identify those individuals who derive greater clinical benefit from statin therapy.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5265071
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- The Lancet
- volume
- 385
- issue
- 9984
- pages
- 2264 - 2271
- publisher
- Elsevier
- external identifiers
-
- pmid:25748612
- wos:000355943500028
- scopus:84934277268
- ISSN
- 1474-547X
- DOI
- 10.1016/S0140-6736(14)61730-X
- language
- English
- LU publication?
- yes
- id
- bd85bff6-00de-42f4-9fcf-a2c816cebc92 (old id 5265071)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25748612?dopt=Abstract
- date added to LUP
- 2016-04-01 10:44:13
- date last changed
- 2024-01-06 23:15:13
@article{bd85bff6-00de-42f4-9fcf-a2c816cebc92, abstract = {{Genetic variants have been associated with the risk of coronary heart disease. In this study, we tested whether or not a composite of these variants could ascertain the risk of both incident and recurrent coronary heart disease events and identify those individuals who derive greater clinical benefit from statin therapy.}}, author = {{Mega, Jessica L and Stitziel, Nathan O and Smith, Gustav and Chasman, Daniel I and Caulfield, Mark J and Devlin, James J and Nordio, Francesco and Hyde, Craig L and Cannon, Christopher P and Sacks, Frank M and Poulter, Neil R and Sever, Peter S and Ridker, Paul M and Braunwald, Eugene and Melander, Olle and Kathiresan, Sekar and Sabatine, Marc S}}, issn = {{1474-547X}}, language = {{eng}}, number = {{9984}}, pages = {{2264--2271}}, publisher = {{Elsevier}}, series = {{The Lancet}}, title = {{Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.}}, url = {{http://dx.doi.org/10.1016/S0140-6736(14)61730-X}}, doi = {{10.1016/S0140-6736(14)61730-X}}, volume = {{385}}, year = {{2015}}, }