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Prevalence of penicillin-non-susceptible Streptococcus pneumoniae in children in day-care centres subjected to an intervention to prevent dispersion.

Ahl, Jonas LU ; Melander, Eva LU ; Odenholt, Inga LU ; Tvetman, Lisa; Thörnblad, Tora; Riesbeck, Kristian LU and Ringberg, Håkan LU (2015) In Infectious Diseases 47(5). p.338-344
Abstract
Background: The aim of this study was to evaluate the day-care interventions implemented in southern Sweden to restrict the dispersion of penicillin-non-susceptible pneumococci with a minimum inhibitory concentration of penicillin G of at least 0.5 mg/l (PNSP0.5). Methods: A retrospective epidemiological study was performed and data from 109 day-care centre interventions from 2000 to 2010 were analysed, including screening results from 7157 individuals. Results: It was found that 42% of the children were carriers of pneumococci and 5% of the screened children were PNSP0.5 carriers. Very few personnel were PNSP0.5 carriers and they were carriers for only a short time. Significantly more contact cases with the same serogroup as the index... (More)
Background: The aim of this study was to evaluate the day-care interventions implemented in southern Sweden to restrict the dispersion of penicillin-non-susceptible pneumococci with a minimum inhibitory concentration of penicillin G of at least 0.5 mg/l (PNSP0.5). Methods: A retrospective epidemiological study was performed and data from 109 day-care centre interventions from 2000 to 2010 were analysed, including screening results from 7157 individuals. Results: It was found that 42% of the children were carriers of pneumococci and 5% of the screened children were PNSP0.5 carriers. Very few personnel were PNSP0.5 carriers and they were carriers for only a short time. Significantly more contact cases with the same serogroup as the index case were found in the first screening and in the same department as the index case, but a substantial number of contact cases were found in adjacent departments. Conclusions: Screening of personnel is not worth the effort. Based on our results, procedures to restrict dispersion of PNSP0.5 in day-care centres could be improved. To find the majority of contact cases with PNSP0.5 an early screening including adjacent departments seems to be the best approach. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infectious Diseases
volume
47
issue
5
pages
338 - 344
publisher
Taylor & Francis
external identifiers
  • pmid:25746603
  • wos:000354612900010
  • scopus:84962575653
ISSN
2374-4243
DOI
10.3109/00365548.2014.994559
language
English
LU publication?
yes
id
4771140f-138d-4060-9443-4b6157f3613c (old id 5265109)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25746603?dopt=Abstract
date added to LUP
2015-04-02 15:06:07
date last changed
2017-10-16 09:46:45
@article{4771140f-138d-4060-9443-4b6157f3613c,
  abstract     = {Background: The aim of this study was to evaluate the day-care interventions implemented in southern Sweden to restrict the dispersion of penicillin-non-susceptible pneumococci with a minimum inhibitory concentration of penicillin G of at least 0.5 mg/l (PNSP0.5). Methods: A retrospective epidemiological study was performed and data from 109 day-care centre interventions from 2000 to 2010 were analysed, including screening results from 7157 individuals. Results: It was found that 42% of the children were carriers of pneumococci and 5% of the screened children were PNSP0.5 carriers. Very few personnel were PNSP0.5 carriers and they were carriers for only a short time. Significantly more contact cases with the same serogroup as the index case were found in the first screening and in the same department as the index case, but a substantial number of contact cases were found in adjacent departments. Conclusions: Screening of personnel is not worth the effort. Based on our results, procedures to restrict dispersion of PNSP0.5 in day-care centres could be improved. To find the majority of contact cases with PNSP0.5 an early screening including adjacent departments seems to be the best approach.},
  author       = {Ahl, Jonas and Melander, Eva and Odenholt, Inga and Tvetman, Lisa and Thörnblad, Tora and Riesbeck, Kristian and Ringberg, Håkan},
  issn         = {2374-4243},
  language     = {eng},
  number       = {5},
  pages        = {338--344},
  publisher    = {Taylor & Francis},
  series       = {Infectious Diseases},
  title        = {Prevalence of penicillin-non-susceptible Streptococcus pneumoniae in children in day-care centres subjected to an intervention to prevent dispersion.},
  url          = {http://dx.doi.org/10.3109/00365548.2014.994559},
  volume       = {47},
  year         = {2015},
}