Clinical validity of flexible spectral imaging color enhancement (FICE) in small-bowel capsule endoscopy : a systematic review and meta-analysis
(2017) In Endoscopy 49(3). p.258-269- Abstract
Patients and methods A comprehensive literature search was conducted. We measured pooled rate of lesion visualization improvement and improvement in lesion detection comparing FICE settings 1 – 3 and WLE, for angioectasias and ulcers/erosions. Pooled results were derived using the random-effects model because of high heterogeneity as measured by I 2. Repeated-measures analysis of variance (ANOVA) was used to measure differences in lesion detection between WLE and the three FICE modes. Results 13 studies were analyzed. All studies used the PillCam SB 1 and/or SB 2 devices. Most used experienced readers. Improvement in delineation had been investigated in 4 studies; in the 3 studies entered into the meta-analysis, using FICE... (More)
Patients and methods A comprehensive literature search was conducted. We measured pooled rate of lesion visualization improvement and improvement in lesion detection comparing FICE settings 1 – 3 and WLE, for angioectasias and ulcers/erosions. Pooled results were derived using the random-effects model because of high heterogeneity as measured by I 2. Repeated-measures analysis of variance (ANOVA) was used to measure differences in lesion detection between WLE and the three FICE modes. Results 13 studies were analyzed. All studies used the PillCam SB 1 and/or SB 2 devices. Most used experienced readers. Improvement in delineation had been investigated in 4 studies; in the 3 studies entered into the meta-analysis, using FICE setting 1, 89 % of angioectasias and 45 % of ulcer/erosions were considered to show improved delineation. For FICE settings 2 and 3, small proportions of images showed improved delineation. Heterogeneity of studies was high with I 2 > 90 % in 4/6 analyses. Lesion detection had been investigated in 10 studies; meta-analysis included 5 studies. Lesion detection did not differ significantly between any of the FICE modes and WLE. Conclusions Overall, the use of the three FICE modes did not significantly improve delineation or detection rate in SBCE. In pigmented lesions, FICE setting 1 performed better in lesion delineation and detection.
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- author
- Yung, Diana E ; Boal Carvalho, Pedro ; Giannakou, Andry ; Kopylov, Uri ; Rosa, Bruno ; Rondonotti, Emanuele ; Toth, Ervin LU ; Koulaouzidis, Anastasios LU and Plevris, John N
- organization
- publishing date
- 2017
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Endoscopy
- volume
- 49
- issue
- 3
- pages
- 258 - 269
- publisher
- Georg Thieme Verlag
- external identifiers
-
- pmid:28122387
- wos:000395642900009
- scopus:85010908744
- ISSN
- 0013-726X
- DOI
- 10.1055/s-0042-122015
- language
- English
- LU publication?
- yes
- id
- 5276c6ff-699b-44ba-9a14-13e434d76125
- date added to LUP
- 2017-02-16 12:02:53
- date last changed
- 2025-04-14 15:21:52
@article{5276c6ff-699b-44ba-9a14-13e434d76125,
abstract = {{<p>Patients and methods A comprehensive literature search was conducted. We measured pooled rate of lesion visualization improvement and improvement in lesion detection comparing FICE settings 1 – 3 and WLE, for angioectasias and ulcers/erosions. Pooled results were derived using the random-effects model because of high heterogeneity as measured by I <sup>2</sup>. Repeated-measures analysis of variance (ANOVA) was used to measure differences in lesion detection between WLE and the three FICE modes. Results 13 studies were analyzed. All studies used the PillCam SB 1 and/or SB 2 devices. Most used experienced readers. Improvement in delineation had been investigated in 4 studies; in the 3 studies entered into the meta-analysis, using FICE setting 1, 89 % of angioectasias and 45 % of ulcer/erosions were considered to show improved delineation. For FICE settings 2 and 3, small proportions of images showed improved delineation. Heterogeneity of studies was high with I <sup>2</sup> > 90 % in 4/6 analyses. Lesion detection had been investigated in 10 studies; meta-analysis included 5 studies. Lesion detection did not differ significantly between any of the FICE modes and WLE. Conclusions Overall, the use of the three FICE modes did not significantly improve delineation or detection rate in SBCE. In pigmented lesions, FICE setting 1 performed better in lesion delineation and detection.</p>}},
author = {{Yung, Diana E and Boal Carvalho, Pedro and Giannakou, Andry and Kopylov, Uri and Rosa, Bruno and Rondonotti, Emanuele and Toth, Ervin and Koulaouzidis, Anastasios and Plevris, John N}},
issn = {{0013-726X}},
language = {{eng}},
number = {{3}},
pages = {{258--269}},
publisher = {{Georg Thieme Verlag}},
series = {{Endoscopy}},
title = {{Clinical validity of flexible spectral imaging color enhancement (FICE) in small-bowel capsule endoscopy : a systematic review and meta-analysis}},
url = {{http://dx.doi.org/10.1055/s-0042-122015}},
doi = {{10.1055/s-0042-122015}},
volume = {{49}},
year = {{2017}},
}