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Clinical validity of flexible spectral imaging color enhancement (FICE) in small-bowel capsule endoscopy : a systematic review and meta-analysis

Yung, Diana E; Boal Carvalho, Pedro; Giannakou, Andry; Kopylov, Uri; Rosa, Bruno; Rondonotti, Emanuele; Toth, Ervin LU ; Koulaouzidis, Anastasios LU and Plevris, John N (2017) In Endoscopy 49(3). p.258-269
Abstract

Patients and methods A comprehensive literature search was conducted. We measured pooled rate of lesion visualization improvement and improvement in lesion detection comparing FICE settings 1 – 3 and WLE, for angioectasias and ulcers/erosions. Pooled results were derived using the random-effects model because of high heterogeneity as measured by I 2. Repeated-measures analysis of variance (ANOVA) was used to measure differences in lesion detection between WLE and the three FICE modes. Results 13 studies were analyzed. All studies used the PillCam SB 1 and/or SB 2 devices. Most used experienced readers. Improvement in delineation had been investigated in 4 studies; in the 3 studies entered into the meta-analysis, using FICE... (More)

Patients and methods A comprehensive literature search was conducted. We measured pooled rate of lesion visualization improvement and improvement in lesion detection comparing FICE settings 1 – 3 and WLE, for angioectasias and ulcers/erosions. Pooled results were derived using the random-effects model because of high heterogeneity as measured by I 2. Repeated-measures analysis of variance (ANOVA) was used to measure differences in lesion detection between WLE and the three FICE modes. Results 13 studies were analyzed. All studies used the PillCam SB 1 and/or SB 2 devices. Most used experienced readers. Improvement in delineation had been investigated in 4 studies; in the 3 studies entered into the meta-analysis, using FICE setting 1, 89 % of angioectasias and 45 % of ulcer/erosions were considered to show improved delineation. For FICE settings 2 and 3, small proportions of images showed improved delineation. Heterogeneity of studies was high with I 2 > 90 % in 4/6 analyses. Lesion detection had been investigated in 10 studies; meta-analysis included 5 studies. Lesion detection did not differ significantly between any of the FICE modes and WLE. Conclusions Overall, the use of the three FICE modes did not significantly improve delineation or detection rate in SBCE. In pigmented lesions, FICE setting 1 performed better in lesion delineation and detection.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Endoscopy
volume
49
issue
3
pages
258 - 269
publisher
Georg Thieme Verlag
external identifiers
  • scopus:85010908744
  • wos:000395642900009
ISSN
0013-726X
DOI
10.1055/s-0042-122015
language
English
LU publication?
yes
id
5276c6ff-699b-44ba-9a14-13e434d76125
date added to LUP
2017-02-16 12:02:53
date last changed
2018-03-18 05:09:37
@article{5276c6ff-699b-44ba-9a14-13e434d76125,
  abstract     = {<p>Patients and methods A comprehensive literature search was conducted. We measured pooled rate of lesion visualization improvement and improvement in lesion detection comparing FICE settings 1 – 3 and WLE, for angioectasias and ulcers/erosions. Pooled results were derived using the random-effects model because of high heterogeneity as measured by I <sup>2</sup>. Repeated-measures analysis of variance (ANOVA) was used to measure differences in lesion detection between WLE and the three FICE modes. Results 13 studies were analyzed. All studies used the PillCam SB 1 and/or SB 2 devices. Most used experienced readers. Improvement in delineation had been investigated in 4 studies; in the 3 studies entered into the meta-analysis, using FICE setting 1, 89 % of angioectasias and 45 % of ulcer/erosions were considered to show improved delineation. For FICE settings 2 and 3, small proportions of images showed improved delineation. Heterogeneity of studies was high with I <sup>2</sup> &gt; 90 % in 4/6 analyses. Lesion detection had been investigated in 10 studies; meta-analysis included 5 studies. Lesion detection did not differ significantly between any of the FICE modes and WLE. Conclusions Overall, the use of the three FICE modes did not significantly improve delineation or detection rate in SBCE. In pigmented lesions, FICE setting 1 performed better in lesion delineation and detection.</p>},
  author       = {Yung, Diana E and Boal Carvalho, Pedro and Giannakou, Andry and Kopylov, Uri and Rosa, Bruno and Rondonotti, Emanuele and Toth, Ervin and Koulaouzidis, Anastasios and Plevris, John N},
  issn         = {0013-726X},
  language     = {eng},
  number       = {3},
  pages        = {258--269},
  publisher    = {Georg Thieme Verlag},
  series       = {Endoscopy},
  title        = {Clinical validity of flexible spectral imaging color enhancement (FICE) in small-bowel capsule endoscopy : a systematic review and meta-analysis},
  url          = {http://dx.doi.org/10.1055/s-0042-122015},
  volume       = {49},
  year         = {2017},
}