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An update on pathophysiological mechanisms related to idiopathic oro-facial pain conditions with implications for management

Forssell, Henrik LU ; Jaaskelainen, S.; List, T.; Svensson, P. and Baad-Hansen, L. (2015) In Journal of Oral Rehabilitation 42(4). p.300-322
Abstract
Chronic oro-facial pain conditions such as persistent idiopathic facial pain (PIFP), atypical odontalgia (AO) and burning mouth syndrome (BMS), usually grouped together under the concept of idiopathic oro-facial pain, remain a diagnostic and therapeutic challenge. Lack of understanding of the underlying pathophysiological mechanisms of these pain conditions is one of the important reasons behind the problems in diagnostic and management. During the last two decades, neurophysiological, psychophysical, brain imaging and neuropathological methods have been systematically applied to study the trigeminal system in idiopathic oro-facial pain. The findings in these studies have provided evidence for neuropathic involvement in the pathophysiology... (More)
Chronic oro-facial pain conditions such as persistent idiopathic facial pain (PIFP), atypical odontalgia (AO) and burning mouth syndrome (BMS), usually grouped together under the concept of idiopathic oro-facial pain, remain a diagnostic and therapeutic challenge. Lack of understanding of the underlying pathophysiological mechanisms of these pain conditions is one of the important reasons behind the problems in diagnostic and management. During the last two decades, neurophysiological, psychophysical, brain imaging and neuropathological methods have been systematically applied to study the trigeminal system in idiopathic oro-facial pain. The findings in these studies have provided evidence for neuropathic involvement in the pathophysiology of PIFP, AO and BMS. The present qualitative review is a joint effort of a group of oro-facial pain specialists and researchers to appraise the literature on idiopathic oro-facial pain with special focus on the currently available studies on their pathophysiological mechanisms. The implications of the findings of these studies for the clinical diagnosis and treatment of idiopathic oro-facial pain conditions are discussed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
persistent idiopathic facial pain, atypical facial pain, atypical, odontalgia, pathophysiology, diagnostics, management
in
Journal of Oral Rehabilitation
volume
42
issue
4
pages
300 - 322
publisher
Wiley-Blackwell
external identifiers
  • wos:000351173800008
  • scopus:84924811408
ISSN
0305-182X
DOI
10.1111/joor.12256
language
English
LU publication?
yes
id
ad7045a1-4e9b-4407-8f73-f89b2cb62a0f (old id 5294032)
date added to LUP
2015-04-24 17:20:06
date last changed
2017-11-19 04:02:41
@article{ad7045a1-4e9b-4407-8f73-f89b2cb62a0f,
  abstract     = {Chronic oro-facial pain conditions such as persistent idiopathic facial pain (PIFP), atypical odontalgia (AO) and burning mouth syndrome (BMS), usually grouped together under the concept of idiopathic oro-facial pain, remain a diagnostic and therapeutic challenge. Lack of understanding of the underlying pathophysiological mechanisms of these pain conditions is one of the important reasons behind the problems in diagnostic and management. During the last two decades, neurophysiological, psychophysical, brain imaging and neuropathological methods have been systematically applied to study the trigeminal system in idiopathic oro-facial pain. The findings in these studies have provided evidence for neuropathic involvement in the pathophysiology of PIFP, AO and BMS. The present qualitative review is a joint effort of a group of oro-facial pain specialists and researchers to appraise the literature on idiopathic oro-facial pain with special focus on the currently available studies on their pathophysiological mechanisms. The implications of the findings of these studies for the clinical diagnosis and treatment of idiopathic oro-facial pain conditions are discussed.},
  author       = {Forssell, Henrik and Jaaskelainen, S. and List, T. and Svensson, P. and Baad-Hansen, L.},
  issn         = {0305-182X},
  keyword      = {persistent idiopathic facial pain,atypical facial pain,atypical,odontalgia,pathophysiology,diagnostics,management},
  language     = {eng},
  number       = {4},
  pages        = {300--322},
  publisher    = {Wiley-Blackwell},
  series       = {Journal of Oral Rehabilitation},
  title        = {An update on pathophysiological mechanisms related to idiopathic oro-facial pain conditions with implications for management},
  url          = {http://dx.doi.org/10.1111/joor.12256},
  volume       = {42},
  year         = {2015},
}