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ICSH guidelines for the standardization of bone marrow immunohistochemistry

Torlakovic, E. E. ; Brynes, R. K. ; Hyjek, E. ; Lee, S. H. ; Kreipe, H. ; Kremer, M. ; Mckenna, R. ; Sadahira, Y. ; Tzankov, A. and Reis, M. , et al. (2015) In International Journal of Laboratory Hematology 37(4). p.431-449
Abstract

Bone marrow (BM) tissue biopsy evaluation, including trephine biopsy and clot section, is an integral part of BM investigation and is often followed by ancillary studies, in particular immunohistochemistry (IHC). IHC provides in situ coupling of morphological assessment and immunophenotype. The number of different IHC tests that can be applied to BM trephine biopsies and the number of indications for IHC testing is increasing concurrently with the development of flow cytometry and molecular diagnostic methods. An international Working Party for the Standardization of Bone Marrow IHC was formed by the International Council for Standardization in Hematology (ICSH) to prepare a set of guidelines for the standardization of BM IHC based on... (More)

Bone marrow (BM) tissue biopsy evaluation, including trephine biopsy and clot section, is an integral part of BM investigation and is often followed by ancillary studies, in particular immunohistochemistry (IHC). IHC provides in situ coupling of morphological assessment and immunophenotype. The number of different IHC tests that can be applied to BM trephine biopsies and the number of indications for IHC testing is increasing concurrently with the development of flow cytometry and molecular diagnostic methods. An international Working Party for the Standardization of Bone Marrow IHC was formed by the International Council for Standardization in Hematology (ICSH) to prepare a set of guidelines for the standardization of BM IHC based on currently available published evidence and modern understanding of quality assurance principles as applied to IHC in general. The guidelines were discussed at the ICSH General Assemblies and reviewed by an international panel of experts to achieve further consensus and represent further development of the previously published ICSH guidelines for the standardization of BM specimens handling and reports.

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publishing date
type
Contribution to journal
publication status
published
keywords
Bone marrow, Immunohistochemistry, Standardization, Trephine biopsy
in
International Journal of Laboratory Hematology
volume
37
issue
4
pages
431 - 449
publisher
Wiley-Blackwell
external identifiers
  • pmid:25977137
  • scopus:84948066248
ISSN
1751-5521
DOI
10.1111/ijlh.12365
language
English
LU publication?
no
id
5321b3e3-473f-43bf-986c-674263e8ff04
date added to LUP
2019-05-22 09:41:56
date last changed
2020-08-26 04:49:36
@article{5321b3e3-473f-43bf-986c-674263e8ff04,
  abstract     = {<p>Bone marrow (BM) tissue biopsy evaluation, including trephine biopsy and clot section, is an integral part of BM investigation and is often followed by ancillary studies, in particular immunohistochemistry (IHC). IHC provides in situ coupling of morphological assessment and immunophenotype. The number of different IHC tests that can be applied to BM trephine biopsies and the number of indications for IHC testing is increasing concurrently with the development of flow cytometry and molecular diagnostic methods. An international Working Party for the Standardization of Bone Marrow IHC was formed by the International Council for Standardization in Hematology (ICSH) to prepare a set of guidelines for the standardization of BM IHC based on currently available published evidence and modern understanding of quality assurance principles as applied to IHC in general. The guidelines were discussed at the ICSH General Assemblies and reviewed by an international panel of experts to achieve further consensus and represent further development of the previously published ICSH guidelines for the standardization of BM specimens handling and reports.</p>},
  author       = {Torlakovic, E. E. and Brynes, R. K. and Hyjek, E. and Lee, S. H. and Kreipe, H. and Kremer, M. and Mckenna, R. and Sadahira, Y. and Tzankov, A. and Reis, M. and Porwit, A.},
  issn         = {1751-5521},
  language     = {eng},
  month        = {01},
  number       = {4},
  pages        = {431--449},
  publisher    = {Wiley-Blackwell},
  series       = {International Journal of Laboratory Hematology},
  title        = {ICSH guidelines for the standardization of bone marrow immunohistochemistry},
  url          = {http://dx.doi.org/10.1111/ijlh.12365},
  doi          = {10.1111/ijlh.12365},
  volume       = {37},
  year         = {2015},
}